Using tree-based machine learning for health studies: literature review and case series

L Hu, L Li - International journal of environmental research and …, 2022 - mdpi.com
Tree-based machine learning methods have gained traction in the statistical and data
science fields. They have been shown to provide better solutions to various research …

Artificial intelligence for dementia prevention

D Newby, V Orgeta, CR Marshall… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION A wide range of modifiable risk factors for dementia have been identified.
Considerable debate remains about these risk factors, possible interactions between them …

Estimating heterogeneous survival treatment effect in observational data using machine learning

L Hu, J Ji, F Li - Statistics in medicine, 2021 - Wiley Online Library
Methods for estimating heterogeneous treatment effect in observational data have largely
focused on continuous or binary outcomes, and have been relatively less vetted with …

Variable selection with missing data in both covariates and outcomes: Imputation and machine learning

L Hu, JY Joyce Lin, J Ji - Statistical methods in medical …, 2021 - journals.sagepub.com
Variable selection in the presence of both missing covariates and outcomes is an important
statistical research topic. Parametric regression are susceptible to misspecification, and as a …

Estimating heterogeneous survival treatment effects of lung cancer screening approaches: A causal machine learning analysis

L Hu, JY Lin, K Sigel, M Kale - Annals of epidemiology, 2021 - Elsevier
ABSTRACT The National Lung Screening Trial (NLST) found that low-dose computed
tomography (LDCT) screening provided lung cancer (LC) mortality benefit compared to …

A flexible approach for causal inference with multiple treatments and clustered survival outcomes

L Hu, J Ji, RD Ennis, JW Hogan - Statistics in medicine, 2022 - Wiley Online Library
When drawing causal inferences about the effects of multiple treatments on clustered
survival outcomes using observational data, we need to address implications of the …

[HTML][HTML] A flexible sensitivity analysis approach for unmeasured confounding with multiple treatments and a binary outcome with application to SEER-Medicare lung …

L Hu, J Zou, C Gu, J Ji, M Lopez… - The annals of applied …, 2022 - ncbi.nlm.nih.gov
In the absence of a randomized experiment, a key assumption for drawing causal inference
about treatment effects is the ignorable treatment assignment. Violations of the ignorability …

A new method for clustered survival data: Estimation of treatment effect heterogeneity and variable selection

L Hu - Biometrical Journal, 2024 - Wiley Online Library
We recently developed a new method random‐intercept accelerated failure time model with
Bayesian additive regression trees (riAFT‐BART) to draw causal inferences about …

A flexible approach for assessing heterogeneity of causal treatment effects on patient survival using large datasets with clustered observations

L Hu, J Ji, H Liu, R Ennis - … journal of environmental research and public …, 2022 - mdpi.com
Personalized medicine requires an understanding of treatment effect heterogeneity.
Evolving toward causal evidence for scenarios not studied in randomized trials necessitates …

A flexible approach for variable selection in large-scale healthcare database studies with missing covariate and outcome data

JYJ Lin, L Hu, C Huang, J Jiayi, S Lawrence… - BMC medical research …, 2022 - Springer
Background Prior work has shown that combining bootstrap imputation with tree-based
machine learning variable selection methods can provide good performances achievable on …