Cardiac toxicity of some echinocandin antifungals

KR Stover, JM Farley, PB Kyle… - Expert opinion on drug …, 2014 - Taylor & Francis
Background: Unexplained cardiovascular decompensation has been observed during
central venous administration of some echinocandins. Objective: The purpose of this study …

Antifungal-associated drug-induced cardiac disease

JD Cleary, KR Stover - Clinical Infectious Diseases, 2015 - academic.oup.com
The etiology of cardiomyopathies are classified into 4 main groupings (dilated, hypertrophic,
restrictive, and idiopathic) and can be mechanistically caused by myocarditis, conduction …

[PDF][PDF] Investigation of the effects of Prosopis farcta plant extract on rat's aorta

K Asadollahi, N Abassi, N Afshar, M Alipour… - J Med Plants …, 2010 - academicjournals.org
Cardiovascular diseases are the main causes of death among developed and developing
countries. More than 50% of cardiovascular deaths are related to coronary artery diseases …

Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels

M Xia, SA Shahane, R Huang, SA Titus, E Shum… - Toxicology and applied …, 2011 - Elsevier
The human ether-a-go-go-related gene (hERG) channel, a member of a family of voltage-
gated potassium (K+) channels, plays a critical role in the repolarization of the cardiac action …

Role of calcium influx through voltage-operated calcium channels and of calcium mobilization in the physiology of Schistosoma mansoni muscle contractions

DL Mendonca-Silva, E Novozhilova, PJR Cobbett… - Parasitology, 2006 - cambridge.org
We tested the hypothesis that voltage-operated Ca2+ channels mediate an extracellular
Ca2+ influx in muscle fibres from the human parasite Schistosoma mansoni and, along with …

[PDF][PDF] Effect of econazole and benzydamine on sensory neurons in culture

S Mathivanan, R de la Torre-Martinez, C Wolf… - J Physiol …, 2016 - jpp.krakow.pl
Econazole is an anti-mycotic agent widely used for the treatment of cutaneous fungal
infections, and for the therapy of vaginal candidiasis. Topical application of this azole is …

[HTML][HTML] Cardiac toxicity of azole antifungals

JD Cleary, KR Stover, J Farley, W Daley, PB Kyle… - 2013 - scirp.org
Cardiac toxicity is an uncommon side effect of anti-fungal therapy. Until the recent reports of
itraconazole (ITZ) associated cardiac failure, amphotericin was the antifungal most …

[PDF][PDF] Vasorelaxatory effect of Vitis vinifera extract on rat aorta

NMK GHARIB, HM Navid, A HEYDARI - 2005 - sid.ir
Reports have shown the antioxidant, hypotensive, hypolipidemic and vasodilatory effects of
grape (VITIS VINIFERA L.) seed extract. We have recently shown the relaxatory effect of …

Extracellular signal-regulated kinase (ERK1/2) contributes to endotoxin-induced hyporeactivity via nitric oxide and prostacyclin production in rat aorta

B Korkmaz, E Ozveren, CK Buharalioglu, B Tunctan - Pharmacology, 2006 - karger.com
This study was conducted to determine if mitogen-activated protein kinases (MAPKs) such
as extracellular signal-regulated kinase (ERK1/2) contribute to endotoxin-induced vascular …

Effects of streptozotocin-induced diabetes and insulin on calcium responsiveness of the rat vas deferens

Y Öztürk, S Aydın - Life sciences, 2006 - Elsevier
In the present study, effects of streptozotocin-induced diabetes and insulin treatment on the
reactivity of rat vas deferens to KCl and calmidazolium, a calmodulin antagonist, were …