• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Aim To provide a contemporary analysis of incidence trends of infective endocarditis (IE)
with its changing epidemiology over the past two decades in Europe. Methods A systematic …

Infective endocarditis in children is a rare entity that poses multiple challenges. A history of
congenital heart disease is the most common risk factor, although in recent years, other …

Background A few years after the publication of the British guidelines, national
recommendations were published by the Swedish Medical Products Agency in October …

Background Infective endocarditis is associated with higher mortality in elderly patients, but
the role of surgery in this group has not been fully evaluated. The aim of this study was to …

Summary In 2023, the European Society of Cardiology (ESC) updated its infective
endocarditis (IE) guidelines strongly endorsing antibiotic prophylaxis (AP) before invasive …

Background It is not clear whether Viridans Group Streptococcal Infective Endocarditis (VGS-
IE) among individuals at high risk is more frequent following bacteraemia caused by …

Importance The association between antibiotic prophylaxis and infective endocarditis after
invasive dental procedures is still unclear. Indications for antibiotic prophylaxis were …

Background Infective endocarditis (IE) is a rare but severe infectious disease. Patients with
IE are treated for weeks in the hospital and have profound impairments to their health. New …

Due to the meagre development of new antibiotics, optimising the use of currently available
antibiotics is important to reduce resistance pressures and to safeguard existing treatment …