Inference of dynamic networks using time-course data

Y Kim, S Han, S Choi, D Hwang - Briefings in bioinformatics, 2014 - academic.oup.com
Cells execute their functions through dynamic operations of biological networks. Dynamic
networks delineate the operation of biological networks in terms of temporal changes of …

Reverse engineering: a key component of systems biology to unravel global abiotic stress cross-talk

S Friedel, B Usadel, N Von Wirén… - Frontiers in Plant …, 2012 - frontiersin.org
Understanding the global abiotic stress response is an important stepping stone for the
development of universal stress tolerance in plants in the era of climate change. Although co …

Global transcriptome analysis in influenza-infected mouse lungs reveals the kinetics of innate and adaptive host immune responses

C Pommerenke, E Wilk, B Srivastava, A Schulze… - PloS one, 2012 - journals.plos.org
An infection represents a highly dynamic process involving complex biological responses of
the host at many levels. To describe such processes at a global level, we recorded gene …

LASSO-driven inference in time and space

V Chernozhukov, W Karl Härdle, C Huang… - The Annals of …, 2021 - projecteuclid.org
LASSO-driven inference in time and space Page 1 The Annals of Statistics 2021, Vol. 49, No.
3, 1702–1735 https://doi.org/10.1214/20-AOS2019 © Institute of Mathematical Statistics …

[HTML][HTML] Subcutaneous infection with S. aureus in mice reveals association of resistance with influx of neutrophils and Th2 response

N Nippe, G Varga, D Holzinger, B Löffler… - Journal of Investigative …, 2011 - Elsevier
Staphylococcus aureus is the leading cause of bacterial skin infection. Once it overcomes
the epithelial barrier, it either remains locally controlled or spreads in the dermis causing soft …

Genome-wide studies of nuclear receptors in cell fate decisions

MA Mendoza-Parra, H Gronemeyer - Seminars in cell & developmental …, 2013 - Elsevier
Nuclear receptors (NRs) are important mediators of the information encoded in the chemical
structure of its corresponding ligand, as they interpret such information in the context of the …

Network Modeling and Control of Dynamic Disease Pathways, Review and Perspectives

YC Hsiao, A Dutta - IEEE/ACM Transactions on Computational …, 2024 - ieeexplore.ieee.org
Dynamic disease pathways are a combination of complex dynamical processes among bio-
molecules in a cell that leads to diseases. Network modeling of disease pathways considers …

Computational Methods for Preprocessing and Classifying Gene Expression Data-Survey

AK AL-Mashanji, SZ AL-Rashi - 2019 4th Scientific …, 2019 - ieeexplore.ieee.org
Microarray experiments generate data sets containing valuable information on the gene
expression levels of millions of genes in the form of a set of biological samples. Inference of …

XGRN: reconstruction of biological networks based on boosted trees regression

GN Dimitrakopoulos - Computation, 2021 - mdpi.com
In Systems Biology, the complex relationships between different entities in the cells are
modeled and analyzed using networks. Towards this aim, a rich variety of gene regulatory …

Influenza A immunomics and public health omics: the dynamic pathway interplay in host response to H1N1 infection

K Dimitrakopoulou, GN Dimitrakopoulos… - Omics: a journal of …, 2014 - liebertpub.com
Towards unraveling the influenza A (H1N1) immunome, this work aims at constructing the
murine host response pathway interactome. To accomplish that, an ensemble of dynamic …