Hereditary spherocytosis (HS) is a disease affecting the red blood cells membrane and
belongs to the congenital hemolytic anemias. The clinical spectrum ranges from …

In this thoroughly revised and updated second edition, a panel of distinguished clinical
researchers from around the world takes stock of the wealth of new knowledge about the …

Objective The spleen is an organ of the defense system with important roles in filtering
functions, phagocytosis, and immunoglobulin production. Septic phenomena are severe …

Splenomegaly results from different abnormal conditions susceptible to drugs. Their
diagnosis is based on a history of exposure to a drug before the spleen enlargement. This …

Background Clinical manifestations of hereditary spherocytosis can be controlled by
splenectomy. The use of this procedure has been restricted due to concerns regarding …

Background When total splenectomy is unavoidable it is important to preserve splenic
function in some form in order to prevent the complications of asplenism. Splenic …

Although splenectomy is helpful in the management of selected patients with chronic
lymphocytic leukemia (CLL), in most cases this procedure is accompanied by a greater …

Background: Over the past 21 years, we have performed more than 200 subtotal
splenectomies, in which the upper splenic pole vascularized only by the gastrosplenic pole …

Background Since 1979, we have been studying subtotal splenectomy. This procedure was
used in over 200 patients to treat splenic trauma, portal hypertension, myeloid metaplasia …

Objective: To determine the immunocompetence of the successfully nonoperatively
managed injured spleen warranting vaccinations for overwhelming postsplenectomy sepsis …