Antimalarial drug resistance and implications for the WHO global technical strategy

MM Ippolito, KA Moser, JBB Kabuya… - Current epidemiology …, 2021 - Springer
Abstract Purpose of Review Five years have passed since the World Health Organization
released its Global Technical Strategy for Malaria (GTS). In that time, progress against …

Geographical spread and structural basis of sulfadoxine-pyrimethamine drug-resistant malaria parasites

R Chaturvedi, J Chhibber-Goel, I Verma… - International Journal for …, 2021 - Elsevier
The global spread of sulfadoxine (Sdx, S) and pyrimethamine (Pyr, P) resistance is attributed
to increasing number of mutations in DHPS and DHFR enzymes encoded by malaria …

Nationwide spatiotemporal drug resistance genetic profiling from over three decades in Indian Plasmodium falciparum and Plasmodium vivax isolates

LP Kojom Foko, G Narang, J Jakhan, S Tamang… - Malaria Journal, 2023 - Springer
Background Drug resistance is a serious impediment to efficient control and elimination of
malaria in endemic areas. Methods This study aimed at analysing the genetic profile of …

[HTML][HTML] CRISPR/Cas advancements for genome editing, diagnosis, therapeutics, and vaccine development for Plasmodium parasites, and genetic engineering of …

L Nourani, AA Mehrizi, S Pirahmadi… - Infection, Genetics and …, 2023 - Elsevier
Malaria as vector-borne disease remains important health concern with over 200 million
cases globally. Novel antimalarial medicines and more effective vaccines must be …

Global scenario of Plasmodium vivax occurrence and resistance pattern

D Kaur, S Sinha, R Sehgal - Journal of Basic Microbiology, 2022 - Wiley Online Library
Malaria caused by Plasmodium vivax is comparatively less virulent than Plasmodium
falciparum, which can also lead to severe disease and death. It shows a wide geographical …

Simultaneous detection of Plasmodium vivax dhfr, dhps, mdr1 and crt-o resistance-associated mutations in the Colombian Amazonian region

JR Cubides, PA Camargo-Ayala, CH Niño… - Malaria journal, 2018 - Springer
Background Malaria continues being a public health problem worldwide. Plasmodium vivax
is the species causing the largest number of cases of malaria in Asia and South America …

[HTML][HTML] Distribution of mutations associated with antifolate and chloroquine resistance among imported Plasmodium vivax in the state of Qatar

D Bansal, A Acharya, PK Bharti… - The American journal …, 2017 - ncbi.nlm.nih.gov
Plasmodium vivax is the most prevalent parasite worldwide, escalating by spread of drug
resistance. Currently, in Qatar, chloroquine (CQ) plus primaquine are recommended for the …

Gene mutations in parasitic diseases Part II: Parasite gene mutations

S Abaza, M El-Tonsy - Parasitologists United Journal, 2017 - puj.journals.ekb.eg
Gene mutation may occur either in the parasite or in the host, which may be beneficial or
harmful for each. As we previously discussed, part I covered causes and types of gene …

Molecular Epidemiology of Malaria and Detection of Anti-malarial Drug Resistance-Associated Markers (PFCRT, PFMDR-1, PFDHFR and PFDHPS) in Hadhramout …

OAA Bamaga - 2017 - search.proquest.com
Malaria, especially Plasmodium falciparum malaria is one of the main causes of mortality
and morbidity worldwide. Yemen is an Eastern Mediterranean country where 68% of its …