Multimodal SHG-2PF Imaging of Microdomain Ca2+-Contraction Coupling in Live Cardiac Myocytes
Rationale: Cardiac myocyte contraction is caused by Ca2+ binding to troponin C, which
triggers the cross-bridge power stroke and myofilament sliding in sarcomeres. Synchronized …
triggers the cross-bridge power stroke and myofilament sliding in sarcomeres. Synchronized …
Sensitized signalling between L-type Ca2+ channels and ryanodine receptors in the absence or inhibition of FKBP12.6 in cardiomyocytes
Aims The heart contraction is controlled by the Ca2+-induced Ca2+ release (CICR) between
L-type Ca2+ channels and ryanodine receptors (RyRs). The FK506-binding protein FKBP12 …
L-type Ca2+ channels and ryanodine receptors (RyRs). The FK506-binding protein FKBP12 …
[HTML][HTML] Sorcin ablation plus β-adrenergic stimulation generate an arrhythmogenic substrate in mouse ventricular myocytes
X Chen, C Weber, ET Farrell, FJ Alvarado… - Journal of molecular and …, 2018 - Elsevier
Sorcin, a penta-EF hand Ca 2+-binding protein expressed in cardiomyocytes, is known to
interact with ryanodine receptors and other Ca 2+ regulatory proteins. To investigate sorcin's …
interact with ryanodine receptors and other Ca 2+ regulatory proteins. To investigate sorcin's …
Ca2+ in the Cleft: Fast and Fluorescent
X Luo, JA Hill - Circulation research, 2014 - Am Heart Assoc
The next leap in Ca2+ imaging technology was introduction of genetically encoded Ca2+
indicators. Genetically encoded Ca2+ indicators offer advantages not achievable with …
indicators. Genetically encoded Ca2+ indicators offer advantages not achievable with …
The Role of Sorcin in Excitation-Contraction Coupling in Normal and Diseased Hearts
X Chen - 2017 - deepblue.lib.umich.edu
Sorcin, a penta-EF hand Ca2+-binding protein, is known to interact with cardiac ryanodine
receptors type 2 (RyR2) and other Ca2+ regulatory proteins, including the L-type Ca2+ …
receptors type 2 (RyR2) and other Ca2+ regulatory proteins, including the L-type Ca2+ …