Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus
SS Gonçalves, ACR Souza, A Chowdhary, JF Meis… - Mycoses, 2016 - Wiley Online Library
The significant increase in the use of antifungal agents, both for the treatment of candidiasis
and invasive aspergillosis and as azole fungicides in agricultural crop protection has …
and invasive aspergillosis and as azole fungicides in agricultural crop protection has …
Epidemiological and Genomic Landscape of Azole Resistance Mechanisms in Aspergillus Fungi
D Hagiwara, A Watanabe, K Kamei… - Frontiers in …, 2016 - frontiersin.org
Invasive aspergillosis is a life-threatening mycosis caused by the pathogenic fungus
Aspergillus. The predominant causal species is Aspergillus fumigatus, and azole drugs are …
Aspergillus. The predominant causal species is Aspergillus fumigatus, and azole drugs are …
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics
Chemogenetic characterization through in vitro evolution combined with whole-genome
analysis can identify antimalarial drug targets and drug-resistance genes. We performed a …
analysis can identify antimalarial drug targets and drug-resistance genes. We performed a …
Inhibiting fungal multidrug resistance by disrupting an activator–mediator interaction
Eukaryotic transcription activators stimulate the expression of specific sets of target genes
through recruitment of co-activators such as the RNA polymerase II-interacting Mediator …
through recruitment of co-activators such as the RNA polymerase II-interacting Mediator …
Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design
The cytochrome P450 enzyme lanosterol 14α-demethylase (LDM) is the target of the azole
antifungals used widely in medicine and agriculture as prophylaxis or treatments of …
antifungals used widely in medicine and agriculture as prophylaxis or treatments of …
Candida glabrata Biofilms: How Far Have We Come?
Infections caused by Candida species have been increasing in the last decades and can
result in local or systemic infections, with high morbidity and mortality. After Candida …
result in local or systemic infections, with high morbidity and mortality. After Candida …
Molecular mechanisms underlying fungicide resistance in citrus postharvest green mold
P Sánchez-Torres - Journal of Fungi, 2021 - mdpi.com
The necrotrophic fungus Penicillium digitatum (Pd) is responsible for the green mold
disease that occurs during postharvest of citrus and causes enormous economic losses …
disease that occurs during postharvest of citrus and causes enormous economic losses …
[HTML][HTML] Facilitators of adaptation and antifungal resistance mechanisms in clinically relevant fungi
MWJ Hokken, BJ Zwaan, WJG Melchers… - Fungal genetics and …, 2019 - Elsevier
Opportunistic fungal pathogens can cause a diverse range of diseases in humans. The
increasing rate of fungal infections caused by strains that are resistant to commonly used …
increasing rate of fungal infections caused by strains that are resistant to commonly used …
A Novel Zn2-Cys6 Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B …
Successful treatment of aspergillosis caused by Aspergillus fumigatus is threatened by an
increasing incidence of drug resistance. This situation is further complicated by the finding …
increasing incidence of drug resistance. This situation is further complicated by the finding …
Antifungal resistance, metabolic routes as drug targets, and new antifungal agents: an overview about endemic dimorphic fungi
JA Parente-Rocha, AM Bailão… - Mediators of …, 2017 - Wiley Online Library
Diseases caused by fungi can occur in healthy people, but immunocompromised patients
are the major risk group for invasive fungal infections. Cases of fungal resistance and the …
are the major risk group for invasive fungal infections. Cases of fungal resistance and the …