Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease that causes
progressive joint damage and can lead to lifelong disability. Numerous studies support the …

Cardiovascular diseases are one of the leading causes of morbidity and mortality in
industrialized countries, and although many processes play a role in the development of …

Background We tested the hypothesis that elevated homocysteine (Hcy) level is causally
associated with increased risk of type 2 diabetes mellitus (T2DM). Results The meta …

Increasing evidence points towards the role of mitochondrial functioning, energy
metabolism, and oxidative stress in migraine. However not all previous research has been …

Chokeberry polyphenols have been suggested to reduce cholesterol and blood pressure
and thus protect against cardiovascular diseases (CVD), but the evidence in humans is …

BACKGROUND: Glycemic excursion is significantly associated with oxidative stress, which
plays a role in the development of chronic complications in type 2 diabetes mellitus (T2DM) …

Background Homocysteine (Hcy) is an independent risk factor for cardiovascular disease,
while mechanisms are unclear. Despite inconsistent and limited, epidemiological and …

Periodontitis induces excessive production of reactive oxygen species in periodontal
lesions. This may impair circulating pro-oxidant/anti-oxidant balance and induce the …

In this meta-analysis study, SNPs were investigated for their association with type 2 diabetes
(T2D) in both Arab and Caucasian ethnicities. A total of 55 SNPs were analyzed, of which 11 …

Methylenetetrahydrofolate reductase (MTHFR) is a critical folate-metabolising enzyme which
requires riboflavin as its co-factor. A common polymorphism (677C→ T) in the MTHFR gene …