The reactivity of aldehydes and ketones carries great potential for multicomponent
heterocyclizations. These reactions are convergent and highly versatile in the development …

The field of Free Radical Chemistry has gained considerable interest in the current scenario.
The formation of free radicals is attributable to different physiochemical factors, radiation …

Today, interest in studies on the search for new drugs to be used in diseases such as
cancer, cardiovascular diseases, neurodegenerative diseases and diabetes, as well as …

Multisubstituted 2-aminothiophenes 1a–c can be readily cyanoacylated via reaction with
cyanoacetic acid in presence of acetic anhydride under a microwave irradiation to form the …

In the present study we have designed a new pharmacophore 'Chalconesemicarbazone'by
pharmacophore hybridization approach of drug design. A series of novel …

Abstract Interaction of 1-(4-morpholinophenyl) ethanone 1 with either malononitrile or ethyl
cyanoacetate 2 afforded Knoevenagel–Cope product 3. In subsequent treatment of 3 with …

DBU-mediated [4+ 1] annulations of donor–acceptor cyclopropanes with carbon disulfide or
thiourea to form 2-aminothiophene-3-carboxylate derivatives have been discovered. This …

The last two decades are characterized by major increases in the incidence of systemic
fungal infections caused by the yeast Candida albicans, particularly in immunocompromised …

In present study, a series of chalconesemicarbazones was synthesized, characterized and
evaluated for their reducing power assay. Most of the compounds were found to be potent …

The activation of elemental sulfur (S8) has been achieved by means of electrogenerated
cyanomethyl anion [easily obtained by galvanostatic reduction from acetonitrile …