Plexiform fibromyxoma is a rare and newly described gastric mesenchymal tumor with only
121 reported cases in the literature. Our understanding of plexiform fibromyxoma requires …

According to the latest statistics from the International Agency for Research on Cancer
(IARC), lung cancer is one of the most lethal malignancies in the world, accounting for …

Understanding disease-associated stem cell abnormality has major clinical implications for
prevention and treatment of human disorders, as well as for regenerative medicine. Here we …

The Hedgehog (HH) signalling pathway is one of the major pathways controlling cell
differentiation and proliferation during human development. This pathway is complex, with …

Background Recently, a novel therapy to treat cancer has been to target cancer stem-like
cells (CSCs). The aim of this study was to investigate the effect of solasodine, a steroidal …

Background Bone metastatic prostate cancer does not completely respond to androgen-
targeted therapy and generally evolves into lethal castration resistant prostate cancer …

The progression of high-grade squamous intraepithelial lesion (HSIL) to invasive cervical
cancer (ICC) is a complex process involving persistent human papillomavirus (HPV) …

Abstract Sonic Hedgehog (Shh) is a morphogen in vertebrate embryos that is also
associated with organ homeostasis in adults. We report here that human platelets, though …

Abstract The Hedgehog (Hh) signaling pathway is essential for maintaining homeostasis
during embryogenesis and in adult tissues. In the liver, dysregulation of this pathway often …

It is being brought to light that smoothened (SMO)‐independent non‐canonical Hedgehog
signaling is associated with the pathogenesis of various cancers. Ursolic acid (UA), a …