The manufacturing of pharmaceutical dosage forms, which has traditionally been a batch-
wise process, is now also transformed into a series of continuous operations. Some …

Complex systems seen either in general engineering practice or economics are subjected to
ever increased uncertainties that are mostly represented as random variables or …

A batch-to-batch model-based iterative optimal control strategy for batch processes is
proposed. To address the difficulties in developing detailed mechanistic models, recurrent …

In the present article, recent developments on modeling and optimization of particulate
polymerization processes are reviewed. A unified population balance approach is described …

In crystallization processes, the need to improve the product quality and to minimize
production cost requires understanding and optimization on how to obtain an appropriate …

This paper presents a comparative analysis of various nonlinear estimation techniques
when applied for output feedback model-based control of batch crystallization processes …

While mathematically sophisticated methods can be used to better understand and improve
processes, the nonlinear nature of food processing models can make their dynamic …

The quadrature method of moments (QMOM) is a recent technique of solving population
balance equations for particle dynamics simulation. In this paper, an alternative solution for …

Polymorphism, a phenomenon in which a substance can have more than one crystal form, is
a frequently encountered phenomenon in pharmaceutical compounds. Different polymorphs …

In this paper, a generalized state-space controller design for the shaping of the output
probability density function (PDF) is presented for non-Gaussian dynamical stochastic …