The plant cell wall—dynamic, strong, and adaptable—is a natural shapeshifter
Mythology is replete with good and evil shapeshifters, who, by definition, display great
adaptability and assume many different forms—with several even turning themselves into …
adaptability and assume many different forms—with several even turning themselves into …
Exploring probiotic effector molecules and their mode of action in gut–immune interactions
Probiotics, live microorganisms that confer health benefits when consumed in adequate
amounts, have gained significant attention for their potential therapeutic applications. The …
amounts, have gained significant attention for their potential therapeutic applications. The …
Updates to the symbol nomenclature for glycans guidelines
Abstract The Symbol Nomenclature for Glycans (SNFG) is a community-curated standard for
the depiction of monosaccharides and complex glycans using various colored-coded …
the depiction of monosaccharides and complex glycans using various colored-coded …
Structures of fructan and galactan from Polygonatum cyrtonema and their utilization by probiotic bacteria
J Zhang, H Chen, L Luo, Z Zhou, Y Wang, T Gao… - Carbohydrate …, 2021 - Elsevier
Polygonatum cyrtonema is a known tonic herb in Chinese Materia Medica, extensively
consumed in China, but the structure and activity of its polysaccharide components remain …
consumed in China, but the structure and activity of its polysaccharide components remain …
Restoring protein glycosylation with GlycoShape
Despite ground-breaking innovations in experimental structural biology and protein structure
prediction techniques, capturing the structure of the glycans that functionalize proteins …
prediction techniques, capturing the structure of the glycans that functionalize proteins …
Glycocalyx regulates the strength and kinetics of cancer cell adhesion revealed by biophysical models based on high resolution label-free optical data
The glycocalyx is thought to perform a potent, but not yet defined function in cellular
adhesion and signaling. Since 95% of cancer cells have altered glycocalyx structure, this …
adhesion and signaling. Since 95% of cancer cells have altered glycocalyx structure, this …
Ruminococcus torques is a keystone degrader of intestinal mucin glycoprotein, releasing oligosaccharides used by Bacteroides thetaiotaomicron
SR Schaus, G Vasconcelos Pereira, AS Luis… - MBio, 2024 - journals.asm.org
Symbiotic interactions between humans and our communities of resident gut microbes
(microbiota) play many roles in health and disease. Some gut bacteria utilize mucus as a …
(microbiota) play many roles in health and disease. Some gut bacteria utilize mucus as a …
Genetically encoded multivalent liquid glycan array displayed on M13 bacteriophage
The central dogma of biology does not allow for the study of glycans using DNA sequencing.
We report a liquid glycan array (LiGA) platform comprising a library of DNA 'barcoded'M13 …
We report a liquid glycan array (LiGA) platform comprising a library of DNA 'barcoded'M13 …
Fine-tuning the spike: role of the nature and topology of the glycan shield in the structure and dynamics of the SARS-CoV-2 S
The dense glycan shield is an essential feature of the SARS-CoV-2 spike (S) architecture,
key to immune evasion and to the activation of the prefusion conformation. Recent studies …
key to immune evasion and to the activation of the prefusion conformation. Recent studies …
The role of GCNT1 mediated O-glycosylation in aggressive prostate cancer
Prostate cancer is the most common cancer in men and a major cause of cancer related
deaths worldwide. Nearly all affected men develop resistance to current therapies and there …
deaths worldwide. Nearly all affected men develop resistance to current therapies and there …