Alzheimer's disease as type 3 diabetes: common pathophysiological mechanisms between Alzheimer's disease and type 2 diabetes

M Michailidis, D Moraitou, DA Tata, K Kalinderi… - International journal of …, 2022 - mdpi.com
Globally, the incidence of type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD)
epidemics is increasing rapidly and has huge financial and emotional costs. The purpose of …

Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers

GB Frisoni, M Boccardi, F Barkhof, K Blennow… - The Lancet …, 2017 - thelancet.com
The diagnosis of Alzheimer's disease can be improved by the use of biological measures.
Biomarkers of functional impairment, neuronal loss, and protein deposition that can be …

EANM procedure guidelines for brain PET imaging using [18F]FDG, version 3

E Guedj, A Varrone, R Boellaard, NL Albert… - European journal of …, 2022 - Springer
The present procedural guidelines summarize the current views of the EANM Neuro-
Imaging Committee (NIC). The purpose of these guidelines is to assist nuclear medicine …

A review on neuroimaging-based classification studies and associated feature extraction methods for Alzheimer's disease and its prodromal stages

S Rathore, M Habes, MA Iftikhar, A Shacklett… - NeuroImage, 2017 - Elsevier
Neuroimaging has made it possible to measure pathological brain changes associated with
Alzheimer's disease (AD) in vivo. Over the past decade, these measures have been …

Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse

H Morton, S Kshirsagar, E Orlov, LE Bunquin… - Free Radical Biology …, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and multiple cognitive impairments. AD is marked by multiple cellular changes …

Arterial spin labeling perfusion of the brain: emerging clinical applications

S Haller, G Zaharchuk, DL Thomas, KO Lovblad… - Radiology, 2016 - pubs.rsna.org
Arterial spin labeling (ASL) is a magnetic resonance (MR) imaging technique used to assess
cerebral blood flow noninvasively by magnetically labeling inflowing blood. In this article, the …

Mitochondria, energy, and metabolism in neuronal health and disease

D Trigo, C Avelar, M Fernandes, J Sá… - FEBS …, 2022 - Wiley Online Library
Mitochondria are associated with various cellular activities critical to homeostasis,
particularly in the nervous system. The plastic architecture of the mitochondrial network and …

Comparison of multiple tau-PET measures as biomarkers in aging and Alzheimer's disease

A Maass, S Landau, SL Baker, A Horng, SN Lockhart… - Neuroimage, 2017 - Elsevier
The recent development of tau-specific positron emission tomography (PET) tracers enables
in vivo quantification of regional tau pathology, one of the key lesions in Alzheimer's disease …

The Centiloid Project: standardizing quantitative amyloid plaque estimation by PET

WE Klunk, RA Koeppe, JC Price, TL Benzinger… - Alzheimer's & …, 2015 - Elsevier
Although amyloid imaging with PiB-PET ([C-11] Pittsburgh Compound-B positron emission
tomography), and now with F-18-labeled tracers, has produced remarkably consistent …

Memory loss in Alzheimer's disease

H Jahn - Dialogues in clinical neuroscience, 2013 - Taylor & Francis
Loss of memory is among the first symptoms reported by patients suffering from Alzheimer's
disease (AD) and by their caretakers. Working memory and long-term declarative memory …