The brain requires a continuous supply of energy in the form of ATP, most of which is
produced from glucose by oxidative phosphorylation in mitochondria, complemented by …

The brain is a highly energy-demanding organ and requires bioenergetic adaptability to
balance normal activity with pathophysiological fuelling of spontaneous recurrent seizures …

Mechanical forces shape cells and tissues during development and adult homeostasis. In
addition, they also signal to cells via mechanotransduction pathways to control cell …

Glucose is the long-established, obligatory fuel for brain that fulfills many critical functions,
including ATP production, oxidative stress management, and synthesis of neurotransmitters …

Microglial cells consume adenosine triphosphate (ATP) during phagocytosis to clear
neurotoxic β-amyloid in Alzheimer's disease (AD). However, the contribution of energy …

Mitochondria are unique organelles that are essential for a variety of cellular processes
including energy metabolism, calcium homeostasis, lipid biosynthesis, and apoptosis …

Brains at rest generate dynamical activity that is highly structured in space and time. We
suggest that spontaneous activity, as in rest or dreaming, underlies top-down dynamics of …

The past 20 years have resulted in unprecedented progress in understanding brain energy
metabolism and its role in health and disease. In this review, which was initiated at the 14th …

The accumulation of aggregated amyloid-β (Aβ) in the brain is the first critical step in the
pathogenesis of Alzheimer's disease (AD), which also includes synaptic impairment …

The mechanisms controlling dynamical patterns in spontaneous brain activity are poorly
understood. Here, we provide evidence that cortical dynamics in the ultra-slow frequency …