Orexins, or hypocretins, are excitatory neuropeptides involved in the regulation of feeding
behavior and the sleep and wakefulness states. Since their discovery, several lines of …

Orexin, also known as hypocretin, is an excitatory neuropeptide secreted by the
hypothalamus. Orexin is divided into orexin-A (OXA) and orexin-B (OXB), which are derived …

The hypothalamus plays a crucial role in the modulation of social behavior by encoding
internal states. The hypothalamic hypocretin/orexin neurons, initially identified as regulators …

Background Growing evidence demonstrates the role of the striatal dopamine system in the
regulation of glucose metabolism. Treatment with dopamine antagonists is associated with …

Orexins are hypothalamic neuropeptides originally discovered to play a role in the
regulation of feeding behaviour. The broad connections of orexin neurons to …

The neuromodulator orexin has been identified as a key factor for motivated arousal
including recent evidence that sleep deprivation-induced enhancement of reward behavior …

Background: The lateral hypothalamic orexin (hypocretin) system has a well-established
role in the motivation for reward. This has particular relevance to substance use disorders …

Intraspecies social interactions are integral for survival and maintenance of society among
all mammalian species. Yet, our understanding of the neural systems and mechanisms …