Abstract Expression of microRNA (miR)-126 is enriched in endothelial cells (ECs) and
endothelial progenitor cells (EPCs). MiR-126 is considered a master regulator of …

Atherosclerosis is characterised by the accumulation of lipid-laden macrophages in
atherosclerotic lesions and occurs preferentially at arterial branching points, which are …

Atherosclerosis, a hyperlipidemia-induced chronic inflammatory process of the arterial wall,
develops preferentially at sites where disturbed laminar flow compromises endothelial cell …

Obesity promotes diverse pathologies, including atherosclerosis and dementia, which
frequently involve vascular defects and endothelial cell (EC) dysfunction. Each organ has …

Background The glomerulus is a specialized capillary bed that is involved in urine
production and BP control. Glomerular injury is a major cause of CKD, which is epidemic …

Lung alveolar type I cells (AT1) and alveolar type II cells (AT2) regulate the structural
integrity and function of alveoli. AT1, covering∼ 95% of the surface area, are responsible for …

Aims Myocardial fibrosis is associated with profound changes in ventricular architecture and
geometry, resulting in diminished cardiac function. There is currently no information on the …

The organization of an integrated coronary vasculature requires the specification of
immature endothelial cells (ECs) into arterial and venous fates based on their localization …

Skeletal (marrow stromal) stem cells (BMSCs) are a group of multipotent cells that reside in
the bone marrow stroma and can differentiate into osteoblasts, chondrocytes and …

Background Irisin is a newly discovered myokine that has been considered a promising
candidate for the treatment of cardiovascular disease through improving endothelial …