How I prevent GVHD in high-risk patients: posttransplant cyclophosphamide and beyond

J Rimando, SR McCurdy, L Luznik - Blood, 2023 - ashpublications.org
Advances in conditioning, graft-versus-host disease (GVHD) prophylaxis and antimicrobial
prophylaxis have improved the safety of allogeneic hematopoietic cell transplantation (HCT) …

Acquired severe aplastic anaemia: how medical therapy evolved in the 20th and 21st centuries

P Scheinberg - British Journal of Haematology, 2021 - Wiley Online Library
The progress in aplastic anaemia (AA) management is one of success. Once an obscure
entity resulting in death in most affected can now be successfully treated with either …

Haploidentical bone marrow transplantation in patients with relapsed or refractory severe aplastic anaemia in the USA (BMT CTN 1502): a multicentre, single-arm …

AE DeZern, M Eapen, J Wu, JA Talano… - The Lancet …, 2022 - thelancet.com
Background Relapsed severe aplastic anaemia is a marrow failure disorder with high
morbidity and mortality. It is often treated with bone marrow transplantation at relapse post …

Transplantation for Fanconi anaemia: lessons learned from Brazil

C Bonfim, S Nichele, G Loth, VAM Funke… - The Lancet …, 2022 - thelancet.com
Fanconi anaemia is a challenging disease to manage, and haematopoietic stem-cell
transplantation (HSCT) is the treatment of choice for the haematological complications …

CMV infection and CMV-specific immune reconstitution following haploidentical stem cell transplantation: an update

XH Luo, Y Zhu, YT Chen, LP Shui, L Liu - Frontiers in Immunology, 2021 - frontiersin.org
Haploidentical stem cell transplantation (haploSCT) has advanced to a common procedure
for treating patients with hematological malignancies and immunodeficiency diseases …

Recent advancements in poor graft function following hematopoietic stem cell transplantation

Y Man, Z Lu, X Yao, Y Gong, T Yang… - Frontiers in …, 2022 - frontiersin.org
Poor graft function (PGF) is a life-threatening complication that occurs after transplantation
and has a poor prognosis. With the rapid development of haploidentical hematopoietic stem …

Fresh or frozen grafts for allogeneic stem cell transplantation: conceptual considerations and a survey on the practice during the COVID-19 pandemic from the EBMT …

N Worel, P Ljungman, ICM Verheggen… - Bone Marrow …, 2023 - nature.com
The COVID-19 pandemic has had a significant impact on medical practices, including the
delivery of allogeneic hematopoietic cell transplantation (HCT). In response, transplant …

Controversies and expectations for the prevention of GVHD: a biological and clinical perspective

B Watkins, KM Williams - Frontiers in Immunology, 2022 - frontiersin.org
Severe acute and chronic graft versus host disease (GVHD) remains a major cause of
morbidity and mortality after allogeneic hematopoietic cell transplantation. Historically, cord …

[HTML][HTML] Impact of conditioning regimen and graft-versus-host disease prophylaxis on the outcome of haploidentical peripheral blood stem cell transplantation for high …

G Kharya, SR Jaiswal, S Bhat, R Raj, SP Yadav… - … and Cellular Therapy, 2023 - Elsevier
Allogenic hematopoietic cell transplantation (HCT) is the best curative approach for patients
with severe aplastic anemia (SAA). The outcomes of HCT from haploidentical family donors …

[HTML][HTML] Comparison of haploidentical stem cell transplantation with post-transplantation cyclophosphamide versus umbilical cord blood transplantation in adult …

Y Onishi, T Mori, H Yamazaki, N Hiramoto… - … and Cellular Therapy, 2023 - Elsevier
Aplastic anemia patients who are refractory to immunosuppressive therapy or with very low
neutrophil counts require allogeneic hematopoietic stem cell transplantation (HSCT) …