The enantioselective synthesis of spirocycles has long been pursued by organic chemists.
Despite their unique 3D properties and presence in several natural products, the difficulty in …

Chiral spirooxindoles are privileged heterocyclic motifs, which are widely found in natural
alkaloids and pharmaceuticals. Moreover, the construction of chiral spiro-cyclic frameworks …

As a powerful synthon, pyrazolone has widely been exploited for the construction of various
chiral pyrazoles/pyrazolones which hold great potential in the development of …

In this study, a new, efficient and stable magnetically heterogeneous nanocatalyst of
Fe3O4@ CPTMO-phenylalanine-Ni via multi steps process starting from simple and cost …

Sustainability in chemical synthesis is a major aspect of the current synthetic endeavors and,
therefore, mimicking the biological process in the laboratory nowadays has the highest …

With a dinuclear zinc-ProPhenol complex as a catalyst, an efficient and novel [3+ 3]
annulation of indoline-2-thiones and isatylidene malononitriles has been successfully …

N‐Boc ketimines derived from pyrazolin‐5‐ones were explored to develop an
unprecedented domino aza‐Friedel–Crafts/N, O‐acetalization reaction with 2‐naphthols …

The present paper reports a highly stereoselective synthesis of spirooxindole-fused
spiropyrazolones through the asymmetric [3+ 2] cyclization reaction of 2-(1-methyl-2 …

This review summarizes the latest developments in asymmetric domino reactions, with the
emphasis on the preparation of spiro compounds. Discussions on the stereoselectivity of the …

A new series of N-Boc ketimines derived from pyrazolin-5-ones have been used as
electrophiles in asymmetric Mannich reactions with pyrazolones. The amino-bis-pyrazolone …