The reactive oxygen species (ROS)-producing enzyme NADPH oxidase (NOX) was first
identified in the membrane of phagocytic cells. For many years, its only known role was in …

Accumulating evidence shows that oxidative stress plays an essential role in the
pathogenesis and progression of many diseases. The imbalance between the production of …

Increased reactive oxygen species (ROS) production has been detected in various cancers
and has been shown to have several roles, for example, they can activate pro-tumourigenic …

Oxygen-derived free radicals, collectively termed reactive oxygen species (ROS), play
important roles in immunity, cell growth, and cell signaling. In excess, however, ROS are …

atherosclerosis, hypertension, cardiac hypertrophy and remodeling, angiogenesis and
collateral formation, stroke, and heart failure. In this review, we discuss in detail the …

Redox signaling regulates physiological self-renewal, proliferation, migration and
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …

Reactive oxygen species (ROS) are considered to be chemically reactive with and
damaging to biomolecules including DNA, protein, and lipid, and excessive exposure to …

The mechanism by which reactive oxygen species (ROS) are produced by tumour cells
remained incompletely understood until the discovery over the last 15 years of the family of …

The progression of colorectal carcinoma (CRC) to invasive and metastatic disease may
involve localized occurrences of epithelial-mesenchymal transition (EMT). However …

Reactive oxygen species (ROS) including superoxide (O2.−) and hydrogen peroxide (H2O2)
are produced endogenously in response to cytokines, growth factors; G-protein coupled …