Toward recovery in schizophrenia: Current concepts, findings, and future research directions

T Onitsuka, Y Hirano, T Nakazawa… - Psychiatry and …, 2022 - Wiley Online Library
Schizophrenia was initially defined as “dementia praecox” by E. Kraepelin, which implies
progressive deterioration. However, recent studies have revealed that early effective …

Neuronal imbalance of excitation and inhibition in schizophrenia: a scoping review of gamma‐band ASSR findings

T Onitsuka, R Tsuchimoto, N Oribe… - Psychiatry and …, 2022 - Wiley Online Library
Recent empirical findings suggest that altered neural synchronization, which is
hypothesized to be associated with an imbalance of excitatory (E) and inhibitory (I) neuronal …

Subcortical volumetric alterations in four major psychiatric disorders: a mega-analysis study of 5604 subjects and a volumetric data-driven approach for classification

N Okada, M Fukunaga, K Miura, K Nemoto… - Molecular …, 2023 - nature.com
Differential diagnosis is sometimes difficult in practical psychiatric settings, in terms of using
the current diagnostic system based on presenting symptoms and signs. The creation of a …

Cerebral cortical structural alteration patterns across four major psychiatric disorders in 5549 individuals

J Matsumoto, M Fukunaga, K Miura, K Nemoto… - Molecular …, 2023 - nature.com
According to the operational diagnostic criteria, psychiatric disorders such as schizophrenia
(SZ), bipolar disorder (BD), major depressive disorder (MDD), and autism spectrum disorder …

Candidate diagnostic biomarkers for neurodevelopmental disorders in children and adolescents: a systematic review

S Cortese, M Solmi, G Michelini, A Bellato… - World …, 2023 - Wiley Online Library
Neurodevelopmental disorders–including attention‐deficit/hyperactivity disorder (ADHD),
autism spectrum disorder, communication disorders, intellectual disability, motor disorders …

Discrimination in the clinical diagnosis between patients with schizophrenia and healthy controls using eye movement and cognitive functions

K Okazaki, K Miura, J Matsumoto… - Psychiatry and …, 2023 - Wiley Online Library
Aim Eye movements and cognitive functions are significantly impaired in patients with
schizophrenia. The authors aimed to develop promising clinical diagnostic markers that fit …

Shared genetic components between metabolic syndrome and schizophrenia: Genetic correlation using multipopulation data sets

R Aoki, T Saito, K Ninomiya… - Psychiatry and …, 2022 - Wiley Online Library
Aim The genetic relationship between schizophrenia (SCZ) and other nonpsychiatric
disorders remains largely unknown. We examined the shared genetic components between …

The effect of ketamine on eye movement characteristics during free-viewing of natural images in common marmosets

Z Polyakova, M Iwase, R Hashimoto… - Frontiers in …, 2022 - frontiersin.org
Various eye movement abnormalities and impairments in visual information processing
have been reported in patients with schizophrenia. Therefore, dysfunction of saccadic eye …

Alterations in subcortical magnetic susceptibility and disease-specific relationship with brain volume in major depressive disorder and schizophrenia

S Shibukawa, H Kan, S Honda, M Wada… - Translational …, 2024 - nature.com
Quantitative susceptibility mapping is a magnetic resonance imaging technique that
measures brain tissues' magnetic susceptibility, including iron deposition and myelination …

Prescription of anticholinergic drugs in patients with schizophrenia: analysis of antipsychotic prescription patterns and hospital characteristics

H Hori, N Yasui-Furukori, N Hasegawa, J Iga… - Frontiers in …, 2022 - frontiersin.org
In several clinical guidelines for schizophrenia, long-term use of anticholinergic drugs is not
recommended. We investigated the characteristics of the use of anticholinergics in patients …