Recent advances in late lung development and the pathogenesis of bronchopulmonary dysplasia
A Madurga, I Mižíková… - American Journal of …, 2013 - journals.physiology.org
In contrast to early lung development, a process exemplified by the branching of the
developing airways, the later development of the immature lung remains very poorly …
developing airways, the later development of the immature lung remains very poorly …
Pathways of cell signaling in hyperoxia
PJ Lee, AMK Choi - Free Radical Biology and Medicine, 2003 - Elsevier
Administration of high concentrations of oxygen (hyperoxia) is a mainstay of supportive
treatment for patients suffering from severe respiratory failure. However, hyperoxia, by …
treatment for patients suffering from severe respiratory failure. However, hyperoxia, by …
Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium
X Zhang, P Shan, M Sasidhar, GL Chupp… - American journal of …, 2003 - atsjournals.org
Therapy with high oxygen concentrations (hyperoxia) is often necessary to treat patients with
respiratory failure. However, hyperoxia may exacerbate the development of acute lung …
respiratory failure. However, hyperoxia may exacerbate the development of acute lung …
Intratracheal transplantation of human umbilical cord blood-derived mesenchymal stem cells dose-dependently attenuates hyperoxia-induced lung injury in neonatal …
YS Chang, SJ Choi, DK Sung, SY Kim… - Cell …, 2011 - journals.sagepub.com
Intratracheal transplantation of human umbilical cord blood (UCB)-derived mesenchymal
stem cells (MSCs) attenuates the hyperoxia-induced neonatal lung injury. The aim of this …
stem cells (MSCs) attenuates the hyperoxia-induced neonatal lung injury. The aim of this …
Timing of umbilical cord blood derived mesenchymal stem cells transplantation determines therapeutic efficacy in the neonatal hyperoxic lung injury
Intratracheal transplantation of human umbilical cord blood (UCB)-derived mesenchymal
stem cells (MSCs) attenuates the hyperoxia-induced neonatal lung injury. The aim of this …
stem cells (MSCs) attenuates the hyperoxia-induced neonatal lung injury. The aim of this …
Inhaled NO improves early pulmonary function and modifies lung growth and elastin deposition in a baboon model of neonatal chronic lung disease
DC McCurnin, RA Pierce, LY Chang… - … of Physiology-Lung …, 2005 - journals.physiology.org
Nitric oxide (NO) serves multiple functions in the developing lung, and pulmonary NO
production is decreased in a baboon model of chronic lung disease (CLD) after premature …
production is decreased in a baboon model of chronic lung disease (CLD) after premature …
Prolonged mechanical ventilation with air induces apoptosis and causes failure of alveolar septation and angiogenesis in lungs of newborn mice
LM Mokres, K Parai, A Hilgendorff… - … of Physiology-Lung …, 2010 - journals.physiology.org
Defective lung septation and angiogenesis, quintessential features of neonatal chronic lung
disease (CLD), typically result from lengthy exposure of developing lungs to mechanical …
disease (CLD), typically result from lengthy exposure of developing lungs to mechanical …
Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death
Epithelial cell death plays a critical role in hyperoxia-induced lung injury. We investigated
the involvement of the autophagic marker microtubule-associated protein-1 light chain-3B …
the involvement of the autophagic marker microtubule-associated protein-1 light chain-3B …
NF-κB signaling in fetal lung macrophages disrupts airway morphogenesis
TS Blackwell, AN Hipps, Y Yamamoto… - The Journal of …, 2011 - journals.aai.org
Bronchopulmonary dysplasia is a common pulmonary complication of extreme prematurity.
Arrested lung development leads to bronchopulmonary dysplasia, but the molecular …
Arrested lung development leads to bronchopulmonary dysplasia, but the molecular …
Postnatal inflammation in the pathogenesis of bronchopulmonary dysplasia
V Bhandari - Birth Defects Research Part A: Clinical and …, 2014 - Wiley Online Library
Exposure to hyperoxia, invasive mechanical ventilation, and systemic/local sepsis are
important antecedents of postnatal inflammation in the pathogenesis of bronchopulmonary …
important antecedents of postnatal inflammation in the pathogenesis of bronchopulmonary …