Soft‐tissue sarcoma in adults: an update on the current state of histiotype‐specific management in an era of personalized medicine

AC Gamboa, A Gronchi… - CA: a cancer journal for …, 2020 - Wiley Online Library
Soft‐tissue sarcomas (STS) are rare tumors that account for 1% of all adult malignancies,
with over 100 different histologic subtypes occurring predominately in the trunk, extremity …

Synovial sarcoma: current concepts and future perspectives

S Stacchiotti, BA Van Tine - Journal of clinical oncology, 2018 - ascopubs.org
Synovial sarcoma (SS) is a rare sarcoma driven by a translocation between SS18 and SSX
1, 2, or 4. With approximately 800 to 1,000 cases a year in the United States, it most …

[HTML][HTML] Soft tissue and visceral sarcomas: ESMO–EURACAN–GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up☆

A Gronchi, AB Miah, AP Dei Tos, N Abecassis… - Annals of …, 2021 - Elsevier
Highlights•This Clinical Practice Guideline provides key recommendations on the
management of soft tissue and visceral sarcomas.•Recommendations have been agreed …

Soft tissue and visceral sarcomas: ESMO–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

PG Casali, N Abecassis, S Bauer, R Biagini… - Annals of …, 2018 - annalsofoncology.org
Soft tissue sarcomas (STSs) gather over 80 histological entities, with even more molecular
subsets, characterised by a low to very low incidence in all populations. The majority of …

Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open …

A Gronchi, S Ferrari, V Quagliuolo, JM Broto… - The Lancet …, 2017 - thelancet.com
Background Previous trials from our group suggested an overall survival benefit with five
cycles of adjuvant full-dose epirubicin plus ifosfamide in localised high-risk soft-tissue …

The proteomic landscape of soft tissue sarcomas

J Burns, CP Wilding, L Krasny, X Zhu… - Nature …, 2023 - nature.com
Soft tissue sarcomas (STS) are rare and diverse mesenchymal cancers with limited
treatment options. Here we undertake comprehensive proteomic profiling of tumour …

Neoadjuvant chemotherapy in high-risk soft tissue sarcomas: final results of a randomized trial from Italian (ISG), Spanish (GEIS), French (FSG), and Polish (PSG) …

A Gronchi, E Palmerini, V Quagliuolo… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To determine whether the administration of histology-tailored neoadjuvant
chemotherapy (HT) was superior to the administration of standard anthracycline plus …

Development and validation of a deep learning model for non–small cell lung cancer survival

Y She, Z Jin, J Wu, J Deng, L Zhang, H Su… - JAMA network …, 2020 - jamanetwork.com
Importance There is a lack of studies exploring the performance of a deep learning survival
neural network in non–small cell lung cancer (NSCLC). Objectives To compare the …

Effect of neoadjuvant chemotherapy plus regional hyperthermia on long-term outcomes among patients with localized high-risk soft tissue sarcoma: the EORTC 62961 …

RD Issels, LH Lindner, J Verweij, R Wessalowski… - JAMA …, 2018 - jamanetwork.com
Importance Patients with soft tissue sarcoma are at risk for local recurrence and distant
metastases despite optimal local treatment. Preoperative anthracycline plus ifosfamide …

Analysis of margin classification systems for assessing the risk of local recurrence after soft tissue sarcoma resection

KR Gundle, L Kafchinski, S Gupta, AM Griffin… - Journal of Clinical …, 2018 - ascopubs.org
Purpose To compare the ability of margin classification systems to determine local
recurrence (LR) risk after soft tissue sarcoma (STS) resection. Methods Two thousand two …