Production of cloned mice and ES cells from adult somatic cells by nuclear transfer: how to improve cloning efficiency?

T Wakayama - Journal of Reproduction and Development, 2007 - jstage.jst.go.jp
Although it has now been 10 years since the first cloned mammals were generated from
somatic cells using nuclear transfer (NT), most cloned embryos usually undergo …

Derivation of human embryonic stem cell lines from parthenogenetic blastocysts

Q Mai, Y Yu, T Li, L Wang, M Chen, S Huang, C Zhou… - Cell research, 2007 - nature.com
Parthenogenesis is one of the main, and most useful, methods to derive embryonic stem
cells (ESCs), which may be an important source of histocompatible cells and tissues for cell …

Understanding pluripotency—how embryonic stem cells keep their options open

BV Johnson, N Shindo, PD Rathjen… - Molecular human …, 2008 - academic.oup.com
Embryonic stem (ES) cells have the capacity to proliferate indefinitely in culture while
maintaining the ability to differentiate to form any of the cells of the body. This unique …

Efficient establishment of mouse embryonic stem cell lines from single blastomeres and polar bodies

S Wakayama, T Hikichi, R Suetsugu, Y Sakaide… - Stem …, 2007 - academic.oup.com
Recently, ES cell lines were established from single blastomeres taken from eight-cell
embryos in mice and humans with success rates of 4% and 2%, respectively, which …

Cryopreservation of hepatocyte microbeads for clinical transplantation

S Jitraruch, A Dhawan, RD Hughes… - Cell …, 2017 - journals.sagepub.com
Intraperitoneal transplantation of hepatocyte microbeads is an attractive option for the
management of acute liver failure. Encapsulation of hepatocytes in alginate microbeads …

Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease

R Sanchez-Pernaute, H Lee, M Patterson… - Brain, 2008 - academic.oup.com
The identity and functional potential of dopamine neurons derived in vitro from embryonic
stem cells are critical for the development of a stem cell-based replacement therapy for …

Correlation of expression and methylation of imprinted genes with pluripotency of parthenogenetic embryonic stem cells

C Li, Z Chen, Z Liu, J Huang, W Zhang… - Human molecular …, 2009 - academic.oup.com
Mammalian parthenogenetic embryos (pE) are not viable due to placental deficiency,
presumably resulting from lack of paternally expressed imprinted genes. Pluripotent …

Essential role of paternal chromatin in the regulation of transcriptional activity during mouse preimplantation development

HT Bui, S Wakayama, E Mizutani, KK Park… - …, 2011 - rep.bioscientifica.com
Bone morphogenetic proteins (BMPs) and their receptors are expressed in ovarian theca
cells (TC) and granulosa cells (GC) and BMPs have been implicated in the regulation of …

Aberrant expression of Igf2/H19 in porcine parthenogenetic fetuses and placentas

X Han, H Ouyang, X Chen, Y Huang, Y Song… - Animal reproduction …, 2013 - Elsevier
The aberrant expression of imprinted genes induces parthenogenetic fetal and placental
dysplasia, thus leading to failures in embryonic development. Igf2 and H19 are co …

Knockdown of H19 enhances differentiation capacity to epidermis of parthenogenetic embryonic stem cells

Y Yin, H Wang, K Liu, F Wang, X Ye… - Current Molecular …, 2014 - ingentaconnect.com
Parthenogenetic embryonic stem (pES) cells are pluripotent stem cells derived from
artificially activated oocytes without embryo destruction, thus eliciting less ethic concerns …