[HTML][HTML] On structural and practical identifiability

FG Wieland, AL Hauber, M Rosenblatt… - Current Opinion in …, 2021 - Elsevier
We discuss issues of structural and practical identifiability of partially observed differential
equations which are often applied in systems biology. The development of mathematical …

Observability and structural identifiability of nonlinear biological systems

AF Villaverde - Complexity, 2019 - Wiley Online Library
Observability is a modelling property that describes the possibility of inferring the internal
state of a system from observations of its output. A related property, structural identifiability …

Bayesian parameter estimation for dynamical models in systems biology

NJ Linden, B Kramer, P Rangamani - PLoS computational biology, 2022 - journals.plos.org
Dynamical systems modeling, particularly via systems of ordinary differential equations, has
been used to effectively capture the temporal behavior of different biochemical components …

Benchmarking tools for a priori identifiability analysis

X Rey Barreiro, AF Villaverde - Bioinformatics, 2023 - academic.oup.com
Motivation The theoretical possibility of determining the state and parameters of a dynamic
model by measuring its outputs is given by its structural identifiability and its observability …

SIAN: software for structural identifiability analysis of ODE models

H Hong, A Ovchinnikov, G Pogudin, C Yap - Bioinformatics, 2019 - academic.oup.com
Biological processes are often modeled by ordinary differential equations with unknown
parameters. The unknown parameters are usually estimated from experimental data. In …

Differential elimination for dynamical models via projections with applications to structural identifiability

R Dong, C Goodbrake, HA Harrington… - SIAM Journal on Applied …, 2023 - SIAM
Elimination of unknowns in a system of differential equations is often required when
analyzing (possibly nonlinear) dynamical systems models, where only a subset of variables …

An integrated framework for building trustworthy data-driven epidemiological models: Application to the COVID-19 outbreak in New York City

S Zhang, J Ponce, Z Zhang, G Lin… - PLoS computational …, 2021 - journals.plos.org
Epidemiological models can provide the dynamic evolution of a pandemic but they are
based on many assumptions and parameters that have to be adjusted over the time the …

Application of a hybrid-driven framework based on sensor optimization placement for the thermal error prediction of the spindle-bearing system

Z Zhan, B Fang, S Wan, Y Bai, J Hong, X Li - Precision Engineering, 2024 - Elsevier
The precise thermal error prediction of spindle-bearing systems (SBSs) necessitates a
comprehensive analysis of information gathered from multi-source sensors. However …

[HTML][HTML] Physiological model-based machine learning for classifying patients with binge-eating disorder (bed) from the oral glucose tolerance test (ogtt) curve

A Procopio, M Rania, P Zaffino, N Cortese… - Computer Methods and …, 2025 - Elsevier
Background and objective: Binge eating disorder (BED) is the most frequent eating disorder,
often confused with obesity, with which it shares several characteristics. Early identification …

Structural identifiability analysis of age-structured PDE epidemic models

M Renardy, D Kirschner, M Eisenberg - Journal of Mathematical Biology, 2022 - Springer
Computational and mathematical models rely heavily on estimated parameter values for
model development. Identifiability analysis determines how well the parameters of a model …