Nucleic acid sequencing
T Hauling, M Kühnemund - US Patent 11,352,667, 2022 - Google Patents
A nucleic acid sequencing method involving contacting a spatially defined target nucleic
acid sequence with N labeled oligonucleotide probes and performing measurements, at …
acid sequence with N labeled oligonucleotide probes and performing measurements, at …
Spatially distinguished, multiplex nucleic acid analysis of biological specimens
J Frisen, P Stahl, J Lundeberg, GM Cann… - US Patent …, 2022 - Google Patents
A method for spatially tagging nucleic acids of a biological specimen, including steps of (a)
providing a solid support comprising different nucleic acid probes that are randomly located …
providing a solid support comprising different nucleic acid probes that are randomly located …
Focal gene expression profiling of stained FFPE tissues with spatial correlation to morphology
E Imler, M Babic, B Seligmann - US Patent 11,091,810, 2021 - Google Patents
Expression profiling of FFPE sample areas smaller than 2 mm2 with single-cell sensitivity,
correlated with tissue microenvironment morphology and neoplastic grade. An automated …
correlated with tissue microenvironment morphology and neoplastic grade. An automated …
Methods for preparing high-resolution spatial arrays
FA Bava - US Patent 12,110,541, 2024 - Google Patents
Provided herein are methods of preparing a spatial array and methods for associating
specific sample analytes with spatial locations in the spatial array. Provided herein are …
specific sample analytes with spatial locations in the spatial array. Provided herein are …
Increasing efficiency of spatial analysis in a biological sample
FA Bava - US Patent 11,732,300, 2023 - Google Patents
Disclosed herein are methods of amplifying an analyte in a biological sample using a
bridging oligonucleotide that hybridizes to a captured analyte. The methods disclosed …
bridging oligonucleotide that hybridizes to a captured analyte. The methods disclosed …
Increasing capture efficiency of spatial assays
FA Bava - US Patent 11,898,205, 2024 - Google Patents
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …
Methods for printing cells and generating arrays of barcoded cells
R Bharadwaj - US Patent 11,702,693, 2023 - Google Patents
US11702693B2 - Methods for printing cells and generating arrays of barcoded cells -
Google Patents US11702693B2 - Methods for printing cells and generating arrays of …
Google Patents US11702693B2 - Methods for printing cells and generating arrays of …
Spatial assays with perturbed cells
EPR Iyer - US Patent 11,732,299, 2023 - Google Patents
US11732299B2 - Spatial assays with perturbed cells - Google Patents US11732299B2 -
Spatial assays with perturbed cells - Google Patents Spatial assays with perturbed cells Info …
Spatial assays with perturbed cells - Google Patents Spatial assays with perturbed cells Info …
Generating capture probes for spatial analysis
Y Yin, EPR Iyer, Z Bent, S Giacomello… - US Patent …, 2023 - Google Patents
2021-06-10 Assigned to 10X GENOMICS, INC. reassignment 10X GENOMICS, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
Spatially distinguished, multiplex nucleic acid analysis of biological specimens
J Frisen, P Stahl, J Lundeberg, GM Cann… - US Patent …, 2021 - Google Patents
A method for spatially tagging nucleic acids of a biological specimen, including steps of (a)
providing a solid support comprising different nucleic acid probes that are randomly located …
providing a solid support comprising different nucleic acid probes that are randomly located …