Advances and challenges in synthetic biology for mosquito control

SC Weng, RA Masri, OS Akbari - Trends in parasitology, 2024 - cell.com
Mosquito-borne illnesses represent a significant global health peril, resulting in
approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are …

A confinable female-lethal population suppression system in the malaria vector, Anopheles gambiae

AL Smidler, JJ Pai, RA Apte, HM Sánchez C… - Science …, 2023 - science.org
Malaria is among the world's deadliest diseases, predominantly affecting Sub-Saharan
Africa and killing over half a million people annually. Controlling the principal vector, the …

Transgene removal using an in cis programmed homing endonuclease via single-strand annealing in the mosquito Aedes aegypti

K Chae, B Contreras, JS Romanowski… - Communications …, 2024 - nature.com
While gene drive strategies have been proposed to aid in the control of mosquito-borne
diseases, additional genome engineering technologies may be required to establish a …

Engineered In Vitro Models to Improve the Mechanistic Understanding and Treatment of Neglected Tropical Diseases Caused by Protozoan Parasites

T Monjure, J Rosero, JA Ruley, AJ Hernandez… - GEN …, 2024 - liebertpub.com
Neglected tropical diseases (NTDs), particularly those caused by trypanosomatid protozoa,
impose a significant global burden, disproportionately affecting underserved communities in …

Evaluating the mating competency of genetically modified male mosquitoes in laboratory conditions

B Contreras, ZN Adelman, K Chae - Frontiers in tropical diseases, 2023 - frontiersin.org
Efforts to eradicate mosquito-borne diseases have increased the demand for genetic control
strategies, many of which involve the release of genetically modified (GM) mosquito males …

[PDF][PDF] A confinable female-lethal population suppression system in the malaria vector, Anopheles gambiae

EJ Gutiérrez, N Thakre, I Antoshechkin, JM Marshall… - 2023 - researchgate.net
Anopheline mosquitoes are responsible for malaria transmission, with the Anopheles
gambiae complex being the most dangerous, contributing to a quarter billion annual cases …

Bioinformatics and Data Analysis in Veterinary Parasitology

SA Attique, QU Ain, MB Said, MS Sajid - Omics Approaches in Veterinary … - taylorfrancis.com
This chapter delves into the pivotal role of bioinformatics in the study and management of
veterinary parasitic diseases. It provides a comprehensive overview of how bioinformatics …