Simultaneous Inference Using Multiple Marginal Models
LA Hothorn, C Ritz, F Schaarschmidt… - Pharmaceutical …, 2024 - Wiley Online Library
This tutorial describes single‐step low‐dimensional simultaneous inference with a focus on
the availability of adjusted p values and compatible confidence intervals for more than just …
the availability of adjusted p values and compatible confidence intervals for more than just …
Group sequential two‐stage preference designs
The two‐stage preference design (TSPD) enables inference for treatment efficacy while
allowing for incorporation of patient preference to treatment. It can provide unbiased …
allowing for incorporation of patient preference to treatment. It can provide unbiased …
Reverse graphical approaches for multiple test procedures
J Gou - Journal of Biopharmaceutical Statistics, 2024 - Taylor & Francis
The graphical approach has been proposed as a general framework for clinical trial designs
involving multiple hypotheses, where decisions are made only based on the observed …
involving multiple hypotheses, where decisions are made only based on the observed …
[PDF][PDF] An introduction to the use of graphical testing procedures in group sequential designs
Y Tymofyeyev - asanjchapter.org
Sequential analysis with a maximum of 2 looks (group sequential design), overall
significance level 2.5%(one-sided). The sample size was calculated for a two-sample …
significance level 2.5%(one-sided). The sample size was calculated for a two-sample …