COVID-19 vaccines: The status and perspectives in delivery points of view

JY Chung, MN Thone, YJ Kwon - Advanced drug delivery reviews, 2021 - Elsevier
Due to the high prevalence and long incubation periods often without symptoms, the severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected millions of individuals …

[HTML][HTML] SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates

GA Poland, IG Ovsyannikova, RB Kennedy - The Lancet, 2020 - thelancet.com
Understanding immune responses to severe acute respiratory syndrome coronavirus 2 is
crucial to understanding disease pathogenesis and the usefulness of bridge therapies, such …

[HTML][HTML] Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19

BJ Ward, P Gobeil, A Séguin, J Atkins, I Boulay… - Nature medicine, 2021 - nature.com
Several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are being
deployed, but the global need greatly exceeds the supply, and different formulations might …

[HTML][HTML] COVID-19 vaccines: rapid development, implications, challenges and future prospects

S Kashte, A Gulbake, SF El-Amin III, A Gupta - Human cell, 2021 - Springer
COVID-19 has affected millions of people and put an unparalleled burden on healthcare
systems as well as economies throughout the world. Currently, there is no decisive therapy …

Self-assembled mRNA vaccines

J Kim, Y Eygeris, M Gupta, G Sahay - Advanced drug delivery reviews, 2021 - Elsevier
Abstract mRNA vaccines have evolved from being a mere curiosity to emerging as COVID-
19 vaccine front-runners. Recent advancements in the field of RNA technology, vaccinology …

[HTML][HTML] Establishment of a well-characterized SARS-CoV-2 lentiviral pseudovirus neutralization assay using 293T cells with stable expression of ACE2 and …

SN Neerukonda, R Vassell, R Herrup, S Liu, T Wang… - PloS one, 2021 - journals.plos.org
Pseudoviruses are useful surrogates for highly pathogenic viruses because of their safety,
genetic stability, and scalability for screening assays. Many different pseudovirus platforms …

Lipid nanoparticles in the development of mRNA vaccines for COVID-19

B Wilson, KM Geetha - Journal of Drug Delivery Science and Technology, 2022 - Elsevier
Abstract Coronavirus disease (COVID-19) was first reported in December 2019, Hubei
Province, China. As on 9th December 2021, severe acute respiratory syndrome-coronavirus …

SARS-CoV-2: Targeted managements and vaccine development

M Bakhiet, S Taurin - Cytokine & growth factor reviews, 2021 - Elsevier
Infection with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) results in
diverse outcomes. The symptoms appear to be more severe in males older than 65 and …

[HTML][HTML] Advances in the design and development of SARS-CoV-2 vaccines

XL Peng, JSY Cheng, HL Gong, MD Yuan… - Military Medical …, 2021 - Springer
Since the end of 2019, coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. The RNA …

[HTML][HTML] The COVID-19 vaccines: recent development, challenges and prospects

Y Yan, Y Pang, Z Lyu, R Wang, X Wu, C You, H Zhao… - Vaccines, 2021 - mdpi.com
The highly infectious coronavirus disease 2019 (COVID-19) associated with the pathogenic
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to become a …