DEAD-box proteins: the driving forces behind RNA metabolism

S Rocak, P Linder - Nature reviews Molecular cell biology, 2004 - nature.com
RNA helicases from the DEAD-box family are found in almost all organisms and have
important roles in RNA metabolism. They are associated with many processes ranging from …

Triple gene block: modular design of a multifunctional machine for plant virus movement

SY Morozov, AG Solovyev - Journal of General Virology, 2003 - microbiologyresearch.org
Many plant virus genera encode a 'triple gene block'(TGB), a specialized evolutionarily
conserved gene module involved in the cell-to-cell and long-distance movement of viruses …

[HTML][HTML] The RNA helicase, nucleotide 5′-triphosphatase, and RNA 5′-triphosphatase activities of Dengue virus protein NS3 are Mg2+-dependent and require a …

D Benarroch, B Selisko, GA Locatelli, G Maga… - Virology, 2004 - Elsevier
The nonstructural protein 3 (NS3) of Dengue virus (DV) is a multifunctional enzyme carrying
activities involved in viral RNA replication and capping: helicase, nucleoside 5 …

The mechanism of ATP-dependent RNA unwinding by DEAD box proteins

M Hilbert, AR Karow, D Klostermeier - 2009 - degruyter.com
DEAD box proteins catalyze the ATP-dependent unwinding of double-stranded RNA
(dsRNA). In addition, they facilitate protein displacement and remodeling of RNA or …

Studies on Three E. coli DEAD-Box Helicases Point to an Unwinding Mechanism Different from that of Model DNA Helicases

T Bizebard, I Ferlenghi, I Iost, M Dreyfus - Biochemistry, 2004 - ACS Publications
DEAD-box proteins participate in various aspects of RNA metabolism in all organisms.
These RNA-dependent ATPases are usually regarded as double-stranded RNA unwinding …

The nonstructural protein 3 protease/helicase requires an intact protease domain to unwind duplex RNA efficiently

DN Frick, RS Rypma, AMI Lam, B Gu - Journal of Biological Chemistry, 2004 - ASBMB
The nonstructural 3 (NS3) protein encoded by the hepatitis C virus possesses both an N-
terminal serine protease activity and a C-terminal 3′–5′ helicase activity. This study …

A DEAD box protein is required for formation of a hidden break in Arabidopsis chloroplast 23S rRNA

K Nishimura, H Ashida, T Ogawa, A Yokota - The Plant Journal, 2010 - Wiley Online Library
In plant chloroplasts, the ribosomal RNA (rRNA) of the large subunit of the ribosome
undergoes post‐maturation fragmentation processing. This processing consists of site …

Interaction between the NH2-terminal domain of eIF4A and the central domain of eIF4G modulates RNA-stimulated ATPase activity

NL Korneeva, EA First, CA Benoit… - Journal of Biological …, 2005 - ASBMB
The eukaryotic translation factor 4A (eIF4A) is a member of DEA (D/H)-box RNA helicase
family, a diverse group of proteins that couples ATP hydrolysis to RNA binding and duplex …

A novel domain within the DEAD-box protein DP103 is essential for transcriptional repression and helicase activity

X Yan, JF Mouillet, Q Ou… - Molecular and Cellular …, 2003 - Am Soc Microbiol
Members of the DEAD-box family of helicases, distinguished by a core characteristic
sequence of Asp-Glu-Ala-Asp, are expressed in a wide range of prokaryotes and eukaryotes …

Characterization of the essential activities of Saccharomyces cerevisiae Mtr4p, a 3′→ 5′ helicase partner of the nuclear exosome

J Bernstein, DN Patterson, GM Wilson… - Journal of Biological …, 2008 - ASBMB
Mtr4p belongs to the Ski2p family of DEVH-box containing proteins and is required for
processing and degradation of a variety of RNA substrates in the nucleus. In particular …