Current advances of nitric oxide in cancer and anticancer therapeutics

J Mintz, A Vedenko, O Rosete, K Shah, G Goldstein… - Vaccines, 2021 - mdpi.com
Nitric oxide (NO) is a short-lived, ubiquitous signaling molecule that affects numerous critical
functions in the body. There are markedly conflicting findings in the literature regarding the …

Therapeutic influence on important targets associated with chronic inflammation and oxidative stress in cancer treatment

M Neganova, J Liu, Y Aleksandrova, S Klochkov, R Fan - Cancers, 2021 - mdpi.com
Simple Summary There is no doubt that the need for new effective methods of cancer
treatment remains challenging, as cancer is the second cause of death based on the …

Regulation of pleiotropic physiological roles of nitric oxide signaling

L Soundararajan, A Dharmarajan, P Samji - Cellular signalling, 2023 - Elsevier
Nitric Oxide (NO) is a highly diffusible, ubiquitous signaling molecule and a free radical that
is naturally synthesized by our body. The pleiotropic effects of NO in biological systems are …

[HTML][HTML] The role and specific mechanism of OCT4 in cancer stem cells: a review

Q Zhang, Z Han, Y Zhu, J Chen… - International journal of …, 2020 - synapse.koreamed.org
Recently, evidences show that cancer stem cells (CSCs) are a type of cancer cell group with
self-renewal and play a huge role in tumor recurrence, metastasis, and drug resistance …

Lung cancer stem cells and cancer stem cell-targeting natural compounds

A Maiuthed, W Chantarawong… - Anticancer …, 2018 - ar.iiarjournals.org
The novel information regarding molecular and translational research have created a
paradigm shift in the understanding of lung cancer biology, revealing the more precise target …

Caveolin-1: a multifaceted driver of breast cancer progression and its application in clinical treatment

XL Qian, YH Pan, QY Huang, YB Shi… - OncoTargets and …, 2019 - Taylor & Francis
Human breast cancer is one of the most frequent cancer diseases and causes of death
among female population worldwide. It appears at a high incidence and has a high …

Nitric oxide system and bronchial epithelium: more than a barrier

MA Bayarri, J Milara, C Estornut, J Cortijo - Frontiers in physiology, 2021 - frontiersin.org
Airway epithelium forms a physical barrier that protects the lung from the entrance of inhaled
allergens, irritants, or microorganisms. This epithelial structure is maintained by tight …

Association between air pollution and primary liver cancer in European and east Asian populations: a Mendelian randomization study

M Sun, M Gao, M Luo, T Wang, T Zhong… - Frontiers in Public …, 2023 - frontiersin.org
Purpose The incidence of primary liver cancer is increasing year by year, with environmental
factors playing a non-negligible role. At present, many studies are still disputing whether air …

Nitric oxide inhibits autophagy and promotes apoptosis in hepatocellular carcinoma

XG Zhang, L Jin, Z Tian, J Wang, Y Yang… - Cancer …, 2019 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the second most common cause of cancer‐related
mortality worldwide. The expression of nitric oxide synthase (NOS) and the inhibition of …

Potential anti-metastasis natural compounds for lung cancer

P Chanvorachote, S Chamni, C Ninsontia… - Anticancer …, 2016 - ar.iiarjournals.org
As lung cancer is the most common malignancy worldwide and high mortalities are the
result of metastasis, novel information surpassing the treatment strategies and therapeutic …