Flavonoids are plant‐derived dietary components with a substantial impact on human
health. Research has expanded massively since it began in the 1930s, and the complex …

Ovarian cancer is known as a serious malignancy that affects women's reproductive tract
and can considerably threat their health. A wide range of molecular mechanisms and …

Aging is a major risk factor in the development of chronic diseases affecting various tissues
including the cardiovascular system, muscle and bones. Age-related diseases are a …

Depression is a serious disorder that affects hundreds of millions of people around the world
and causes poor quality of life, problem behaviors, and limitations in activities of daily living …

Quercetin is regarded as a potential hepatoprotective agent in the treatment of acute liver
injury. However, the underlying mechanism of how quercetin to protect against …

Introduction Acetaminophen (APAP) as an analgesic and antipyretic drug can result to liver
damages while using more than 4 g/day. Therefore, APAP toxicity causes the liver to …

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are key producer
of reactive oxygen species in liver cells. Hepatic stellate cells (HSCs) and Kupffer cells (KCs) …

Due to high oxygen consumption, the brain is particularly vulnerable to oxidative stress,
which is considered an important element in the etiopathogenesis of several mental …

Abstract Quercetin (3, 3′, 4′, 5, 7‐pentahydroxyflavone), a flavonoid, is widely found in
fruits and vegetables and exerts broad‐spectrum pharmacological effects in the liver. Many …

Cholestasis is a common manifestation of decreased bile flow in various liver diseases. It
results in fibrosis and even cirrhosis without proper treatment. It is believed that a wide range …