In the rapidly moving proteomics field, a diverse patchwork of data analysis pipelines and
algorithms for data normalization and differential expression analysis is used by the …

We present a flexible, user-friendly R package called protti for comprehensive quality
control, analysis and interpretation of quantitative bottom-up proteomics data. protti supports …

Vitamin D deficiency and dyslipidemia have substantial implications for human health
globally. Vitamin D is essential for bone metabolism and immune modulation, and its …

The selection of plant genotypes with improved productivity and tolerance to environmental
constraints has always been a major concern in plant breeding. Classical approaches …

Expansion of the glutamine tract (poly-Q) in the protein huntingtin (HTT) causes the
neurodegenerative disorder Huntington's disease (HD). Emerging evidence suggests that …

Bottom-up proteomics analyses have been proved over the last years to be a powerful tool
in the characterization of the proteome and are crucial for understanding cellular and …

Motivation Mass spectrometry-based system proteomics allows identification of dysregulated
protein hubs and associated disease-related features. Obtaining differentially expressed …

Abstract The Cystic Fibrosis Transmembrane conductance Regulator (CFTR) is an ion
channel primarily studied in the context of epithelial fluid homeostasis in the lung. CFTR is …

Introduction: Vitamin D deficiency is highly prevalent in Qatar. Vitamin D exerts immune-
modulatory effects leading to reduced inflammation. Therefore, vitamin D deficiency is …