MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

The molecular mechanisms and genetic programs required for cancer metastasis are
sometimes overlapping, but components are clearly distinct from those promoting growth of …

BRMS1L (breast cancer metastasis suppressor 1 like, BRMS1-like) is a component of Sin3A–
histone deacetylase (HDAC) co-repressor complex that suppresses target gene …

Breast cancer is a systemic disease characterized by early dissemination of tumor cells to
distant organs. In this foreign environment, tumor cells may stay in a dormant state as single …

Although protein kinase D3 (PKD3) has been shown to contribute to prostate cancer cell
growth and survival, the role of PKD in prostate cancer cell motility remains unclear. Here …

Abstract Kaposi's sarcoma (KS), a highly invasive and angiogenic tumor of endothelial
spindle-shaped cells, is the most common AIDS-associated cancer caused by KS …

Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis without affecting
primary tumorigenesis. The regulatory mechanism of BRMS1 at the protein level has not …

The majority of clinical deaths in patients with triple-negative breast cancer (TNBC) are due
to chemoresistance and aggressive metastases, with high prevalence in younger women of …

ING4 has been previously shown to play important roles in regulating apoptosis, cell cycle
progress, cell migration, and invasion. In this study, we investigated the impact of ING4 on …

Breast carcinoma metastasis suppressor gene 1 (BRMS1) encodes an inhibitor of
metastasis and is reported in many types of tumor metastasis. However, the mechanism of …