Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain
Abstract Polycomb repressive complex 1 (PRC1) is an essential chromatin-modifying
complex that monoubiquitinates histone H2A and is involved in maintaining the repressed …
complex that monoubiquitinates histone H2A and is involved in maintaining the repressed …
Polyether complexes of groups 13 and 14
CLB Macdonald - Chemical Society Reviews, 2016 - pubs.rsc.org
Notable aspects of the chemistry of complexes of polyether ligands including crown ethers,
cryptands, glycols, glymes, and related polyether ligands with heavier group 13 and 14 …
cryptands, glycols, glymes, and related polyether ligands with heavier group 13 and 14 …
Dual FGF-2 and intergrin α5β1 signaling mediate GRAF-induced RhoA inactivation in a model of breast cancer dormancy
J Barrios, R Wieder - Cancer Microenvironment, 2009 - Springer
Interactions with the bone marrow stroma regulate dormancy and survival of breast cancer
micrometastases. In an in vitro model of dormancy in the bone marrow, we previously …
micrometastases. In an in vitro model of dormancy in the bone marrow, we previously …
Identification and Characterization of anEntamoeba histolytica Upstream Regulatory Element 3 Sequence-specific DNA-binding Protein Containing EF-hand Motifs
CA Gilchrist, CF Holm, MA Hughes… - Journal of Biological …, 2001 - ASBMB
The hgl5 gene of Entamoeba histolytica is negatively regulated through the upstream
regulatory element 3 (URE3) DNA motif TATTCTATT. This motif is also present and …
regulatory element 3 (URE3) DNA motif TATTCTATT. This motif is also present and …
Identification of a GTP-bound Rho specific scFv molecular sensor by phage display selection
M Goffinet, P Chinestra, I Lajoie-Mazenc… - BMC …, 2008 - Springer
Abstract Background The Rho GTPases A, B and C proteins, members of the Rho family
whose activity is regulated by GDP/GTP cycling, function in many cellular pathways …
whose activity is regulated by GDP/GTP cycling, function in many cellular pathways …
Structure of the BH domain from graf and its implications for Rho GTPase recognition
KL Longenecker, B Zhang, U Derewenda… - Journal of Biological …, 2000 - ASBMB
Cellular signaling by small G-proteins is down-regulated by GTPase-activating proteins
(GAPs), which increase the rate of GTP hydrolysis. The GTPase regulator associated with …
(GAPs), which increase the rate of GTP hydrolysis. The GTPase regulator associated with …
Conformation of the γ Subunit at the γ−ε−c Interface in the Complete Escherichia coli F1-ATPase Complex by Site-Directed Spin Labeling
SH Andrews, YB Peskova, MK Polar, VB Herlihy… - Biochemistry, 2001 - ACS Publications
Structure− function relationships of the γ− ε− c subunit interface of FOF1 ATP synthase, a
region of subunit interactions important in coupling between catalysis and transport, were …
region of subunit interactions important in coupling between catalysis and transport, were …
Conception et obtention d'un anticorps spécifique des formes activées des Rho GTPases
M Goffinet - 2007 - theses.fr
Résumé Les protéines Rho A, B et C dont l'activité est régulée par l'échange GDP/GTP
seraient impliquées dans la tumorigenèse. Même si la surexpression dans les tumeurs des …
seraient impliquées dans la tumorigenèse. Même si la surexpression dans les tumeurs des …