Cancer stem cells—origins and biomarkers: perspectives for targeted personalized therapies

L Walcher, AK Kistenmacher, H Suo, R Kitte… - Frontiers in …, 2020 - frontiersin.org
The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …

Emerging roles of CD133 in the treatment of gastric cancer, a novel stem cell biomarker and beyond

A Soleimani, P Dadjoo, A Avan, S Soleimanpour… - Life Sciences, 2022 - Elsevier
Gastric cancer (GC) is an aggressive disease with one of the highest mortality rates in the
world. In the early stage, most patients are asymptomatic and early diagnosis is difficult …

DYNC1I1 promotes the proliferation and migration of gastric cancer by up-regulating IL-6 expression

LB Gong, T Wen, Z Li, X Xin, XF Che, J Wang… - Frontiers in …, 2019 - frontiersin.org
Gastric cancer is one of the top five malignant tumors worldwide. At present, the molecular
mechanisms of gastric cancer progression are still not completely clear. Cytoplasmic dynein …

The adenosine-A2a receptor regulates the radioresistance of gastric cancer via PI3K-AKT-mTOR pathway

G Liu, S Yang, Y Liu, Y Xu, H Qiu, J Sun, J Song… - International Journal of …, 2022 - Springer
Background Radiotherapy is a key strategy in gastric cancer (GC) treatment. However,
radioresistance remains a serious concern. It is unclear whether the accumulation of …

[HTML][HTML] Immunohistochemical Expression of CD90, CD133, and TPM1 in Relation to Gastric Cancer and H. pylori Association

NS Gamal, S Ashraf, N Hesham… - Asian Pacific Journal …, 2023 - ncbi.nlm.nih.gov
Background: Gastric cancer (GC) is the second most common cause of cancer-related death
worldwide. Multiple malignancies overexpress CD90, making it a helpful diagnostic and …

A novel approach for transforming breast cancer stem cells into endothelial cells

QQ Mao, XC Ji, JN Zhang… - Experimental and …, 2023 - spandidos-publications.com
Tumor vascular endothelial cells play a pivotal in the tumor microenvironment, influencing
the proliferation, invasion, and metastasis of tumor progression. The present study …

Helicobacter pylori targets in AGS human gastric adenocarcinoma: In situ proteomic profiling and systematic analysis

JS Yang, CY Kang, CH Su, CJ Chen, YJ Chiu… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: Helicobacter pylori, a gram-negative bacterium, causes chronic stomach
diseases in humans. Heat shock proteins (HSPs) are involved in cell integrity, cell growth …

Diagnostic and Prognostic Significance of Cancer Stem Cell Surface Markers

S Aktar, S Islam, V Gopalan, AK Lam… - Cancer Stem Cells: Basic …, 2023 - Springer
Cancer stem cells (CSCs) are a specific type of cancer cell that can both self-renew and
differentiate, playing a key role in cancer development and progression. Existing clinical …

[HTML][HTML] Prevalence of Helicobacter pylori Genes (CagA, BabA, and HomB) with Stem Cell Markers (LGR5 and CD133) in Severity of Gastric Disease

SK Abdullah, WA Bakir, MI Alsikafi - Medical Journal of Babylon, 2024 - journals.lww.com
Background: Gastritis is commonly caused by Helicobacter pylori, which colonizes the
mucosa of the gastric epithelium in more than half the population worldwide. It adheres to …

Expression and clinicopathologic significance of aldehyde dehydrogenase 1 and human epidermal growth factor receptor in gastric adenocarcinoma

SHI Qing-fang, LI Ling-ling, Y Jun-e… - Jie Fang Jun Yi Xue …, 2019 - search.proquest.com
Objective To investigate the expression of aldehyde dehydrogenase 1 (ALDH1) and human
epidermal growth factor receptor (HER-2) in human gastric cancer tissues, and analyze its …