Currently, there is no completely effective therapy available for metastatic
phaeochromocytomas (PCCs) and paragangliomas. In this study, we explore new molecular …

In recent years, cancer genomics has provided new insights into genetic alterations and
signaling pathways involved in thyroid cancer. However, the picture of the molecular …

Purpose: Mitochondrial glycerophosphate dehydrogenase (MGPDH) is the key enzyme
connecting oxidative phosphorylation (OXPHOS) and glycolysis as well as a target of the …

There is no effective treatment for patients with poorly differentiated papillary thyroid cancer
or anaplastic thyroid cancer (ATC). Anlotinib, a multi-kinase inhibitor, has already shown …

Autoimmune thyroid diseases (AITDs), ie, Graves' disease (GD) and Hashimoto thyroiditis
(HT), are the most prevalent organ-specific autoimmune diseases, but their pathogenesis is …

STATs constitute a large family of transcription activators and transducers of signals that
have an important role in many cell functions as regulation of proliferation and differentiation …

Parathyroid carcinoma (PaC) is a rare cause of primary hyperparathyroidism. Though the
loss of the oncosuppressor CDC73/HRPT2 gene product, parafibromin, has been involved …

Neutrophils are key effector cells that orchestrate inflammatory responses in the tumor
microenvironment. Although neutrophil extracellular DNA traps (NETs) entrap and kill …

The incidence of thyroid cancer is growing rapidly during the past decades worldwide.
Although most thyroid tumors are curable, some patients diagnosed with distant metastases …

Curcumin, a polyphenolic compound, is a well-known anticancer agent, although its poor
bioavailability remains a big concern. Recent studies suggest that autophagy-targeted …