Diagnosis of neonatal sepsis: the past, present and future

IH Celik, M Hanna, FE Canpolat, M Pammi - Pediatric research, 2022 - nature.com
Sepsis remains a significant cause of neonatal mortality and morbidity, especially in low-and
middle-income countries. Neonatal sepsis presents with nonspecific signs and symptoms …

Biomarkers for diagnosis of neonatal sepsis: a literature review

D Sharma, N Farahbakhsh, S Shastri… - The Journal of Maternal …, 2018 - Taylor & Francis
Sepsis is an important cause of mortality and morbidity in neonatal populations. There has
been constant search of an ideal sepsis biomarker that have high sensitivity, specificity …

Neutrophil dysregulation during sepsis: an overview and update

XF Shen, K Cao, J Jiang, WX Guan… - Journal of cellular and …, 2017 - Wiley Online Library
Sepsis remains a leading cause of death worldwide, despite advances in critical care, and
understanding of the pathophysiology and treatment strategies. No specific therapy or drugs …

Translational research and biomarkers in neonatal sepsis

JR Delanghe, MM Speeckaert - Clinica chimica acta, 2015 - Elsevier
As neonatal sepsis is a severe condition, there is a call for reliable biomarkers to
differentiate between infected and noninfected newborns. Although blood culture has been …

Biomarkers for sepsis: what is and what might be?

BM Biron, A Ayala, JL Lomas-Neira - Biomarker insights, 2015 - journals.sagepub.com
Every year numerous individuals develop the morbid condition of sepsis. Therefore, novel
biomarkers that might better inform clinicians treating such patients are sorely needed …

Biomarkers of neonatal sepsis: where we are and where we are going

G Boscarino, R Migliorino, G Carbone, G Davino… - Antibiotics, 2023 - mdpi.com
Neonatal sepsis is a bacterial bloodstream infection leading to severe clinical manifestations
frequently associated with death or irreversible long-term deficits. Antibiotics are the drug of …

Red blood cell distribution width and neutrophil/lymphocyte ratio are positively correlated with disease activity in primary Sjögren's syndrome

ZD Hu, Y Sun, J Guo, YL Huang, BD Qin, Q Gao… - Clinical …, 2014 - Elsevier
Objective The red blood cell distribution width (RDW) and neutrophil/lymphocyte ratio (NLR)
are increased in various inflammation related diseases, but their clinical significance in …

Biomarkers for the diagnosis of neonatal sepsis and necrotizing enterocolitis: Clinical practice guidelines

M Gilfillan, V Bhandari - Early human development, 2017 - Elsevier
Sepsis and necrotizing enterocolitis are major contributors to morbidity and mortality in
neonates, especially in those born preterm. While therapeutic interventions are available for …

Acute-on-chronic liver failure (ACLF) in 2022: have novel treatment paradigms already arrived?

N Abbas, N Rajoriya, AM Elsharkawy… - Expert review of …, 2022 - Taylor & Francis
Introduction Acute-on-chronic failure (ACLF) is a recognized syndrome in patients with
chronic liver disease and is characterized by acute decompensation, organ failure (s), and a …

[PDF][PDF] Dynamic monitoring of monocyte HLA-DR expression for the diagnosis, prognosis, and prediction of sepsis

Y Zhuang, H Peng, Y Chen, S Zhou… - Front Biosci (Landmark …, 2017 - article.imrpress.com
Sepsis, an under-recognized health problem, is a major cause of death. More than 750,000
individuals develop sepsis annually, of whom 215,000 die of the disease. Clinical and …