Immune infiltration and prostate cancer

A Strasner, M Karin - Frontiers in oncology, 2015 - frontiersin.org
It is becoming increasingly clear that inflammation influences prostate cancer (PCa)
development and that immune cells are among the primary drivers of this effect. This …

Current knowledge of the potential links between inflammation and prostate cancer

T Cai, R Santi, I Tamanini, IC Galli, G Perletti… - International journal of …, 2019 - mdpi.com
Inflammation is inherent in prostatic diseases and it is now accepted that it may facilitate
cellular proliferation in both benign and malignant conditions. The strong relationship …

Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial

B Gurel, MS Lucia, IM Thompson Jr, PJ Goodman… - … , biomarkers & prevention, 2014 - AACR
Background: Chronic inflammation is hypothesized to influence prostate cancer
development, although a definitive link has not been established. Methods: Prostate cancer …

The role of prostatic inflammation in the development and progression of benign and malignant diseases

G Gandaglia, E Zaffuto, N Fossati… - Current opinion in …, 2017 - journals.lww.com
Men with BPH-related lower urinary tract symptoms and chronic prostatic inflammation
should be considered at increased risk of symptom progression and acute urinary retention …

A prospective study of chronic inflammation in benign prostate tissue and risk of prostate cancer: linked PCPT and SELECT cohorts

EA Platz, I Kulac, JR Barber, CG Drake, CE Joshu… - … Biomarkers & Prevention, 2017 - AACR
Background: We leveraged two trials to test the hypothesis of an inflammation–prostate
cancer link prospectively in men without indication for biopsy. Methods: Prostate Cancer …

The role of prostate inflammation and fibrosis in lower urinary tract symptoms

WA Bushman, TJ Jerde - American Journal of Physiology …, 2016 - journals.physiology.org
Lower urinary tract symptoms (LUTS) in aging men are extremely common. They have
historically been attributed to benign prostatic hyperplasia (BPH), enlargement of the …

Exploring the role of the inflammasomes on prostate cancer: Interplay with obesity

JM Pérez-Gómez, AJ Montero-Hidalgo… - Reviews in Endocrine …, 2023 - Springer
Obesity is a weight-related disorder characterized by excessive adipose tissue growth and
dysfunction which leads to the onset of a systemic chronic low-grade inflammatory state …

Inflammation and prostate cancer: a multidisciplinary approach to identifying opportunities for treatment and prevention

L Huang, MJ LaBonte, SG Craig, SP Finn, EH Allott - Cancers, 2022 - mdpi.com
Simple Summary Prostatitis, or the inflammation of the prostate, is frequently observed in the
clinic and by research studies, but its relevance to a man's risk of being diagnosed with …

The association between prostatitis and prostate cancer: systematic review and meta-analysis

G Perletti, E Monti, V Magri, T Cai, A Cleves… - Archivio Italiano di …, 2017 - biblio.ugent.be
Objective: The main outcome of this review was the association between a history of clinical
chronic prostatitis (NIH category II or III) and a histologically confirmed diagnosis of prostate …

Neutrophil, lymphocyte and platelet counts, and risk of prostate cancer outcomes in white and black men: results from the SEARCH database

AC Vidal, LE Howard, A de Hoedt… - Cancer Causes & …, 2018 - Springer
Purpose Systemic inflammation, as measured by C-reactive protein, has been linked with
poor prostate cancer (PC) outcomes, predominantly in white men. Whether other immune …