Autoantibodies directed against a variety of nuclear, cytoplasmic and extracellular
autoantigens are a serological hallmark of systemic sclerosis. This review provides an …

The term undifferentiated connective tissue disease (UCTD) refers to unclassifiable systemic
autoimmune diseases which share clinical and serological manifestations with definite …

Objectives The EULAR (European League Against Rheumatism) Scleroderma Trials and
Research Group (EUSTAR) has identified preliminary criteria for very early diagnosis of …

Objective. To determine the prevalence of systemic sclerosis (SSc) overlap syndrome and
autoantibody profile in a large single-center cohort. Methods. SSc diagnoses, subsets, and …

Objective To determine the relationships between systemic sclerosis (SSc)–related
autoantibodies, as well as their clinical associations, in a well‐characterized Australian …

Abstract Background Systemic sclerosis (SSc) is a rare autoimmune disease characterized
by fibrosis of the skin and the involvement of multiple internal organs. Previous studies …

Scleroderma renal crisis (SRC) is an uncommon but still life-threatening manifestation of
systemic sclerosis (SSc). The incidence of SRC has decreased in the last few decades …

OBJECTIVES: There is a need for standardization in systemic sclerosis (SSc) management.
METHODS: SSc experts (n= 117) were sent 3 surveys to gain consensus for SSc …

Objective Studies assessing the prevalence of anti–RNA polymerase III (anti–RNAP III)
antibodies in systemic sclerosis (SSc) have yielded a wide range of results. The aim of the …

Background The pathogenesis and etiology of systemic sclerosis (SSc) are complex and
poorly understood. To date, several studies have demonstrated that the activation of the …