Artificial intelligence in neurodegenerative diseases: A review of available tools with a focus on machine learning techniques

AM Tăuţan, B Ionescu, E Santarnecchi - Artificial intelligence in medicine, 2021 - Elsevier
Neurodegenerative diseases have shown an increasing incidence in the older population in
recent years. A significant amount of research has been conducted to characterize these …

Speech and language impairments in behavioral variant frontotemporal dementia: a systematic review

A Geraudie, P Battista, AM García, IE Allen… - Neuroscience & …, 2021 - Elsevier
Although behavioral variant frontotemporal dementia (bvFTD) is classically defined by
behavioral and socio-emotional changes, impairments often extend to other cognitive …

Clinical measures of bulbar dysfunction in ALS

Y Yunusova, EK Plowman, JR Green, C Barnett… - Frontiers in …, 2019 - frontiersin.org
Bulbar impairment represents a hallmark feature of Amyotrophic Lateral Sclerosis (ALS) that
significantly impacts survival and quality of life. Speech and swallowing dysfunction are key …

Communication impairment in Parkinson's disease: Impact of motor and cognitive symptoms on speech and language

KM Smith, DN Caplan - Brain and language, 2018 - Elsevier
Communication impairment is common in Parkinson's disease (PD) and may have both
motor speech control and cognitive-linguistic underpinnings. The neurobiology of …

“You say severe, I say mild”: Toward an empirical classification of dysarthria severity

KL Stipancic, KM Palmer, HP Rowe, Y Yunusova… - Journal of Speech …, 2021 - ASHA
Purpose: The main purpose of this study was to create an empirical classification system for
speech severity in patients with dysarthria secondary to amyotrophic lateral sclerosis (ALS) …

Clinical and radiological markers of extra-motor deficits in amyotrophic lateral sclerosis

F Christidi, E Karavasilis, M Rentzos, N Kelekis… - Frontiers in …, 2018 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is now universally recognized as a complex multisystem
disorder with considerable extra-motor involvement. The neuropsychological manifestations …

Design and results of a smartphone‐based digital phenotyping study to quantify ALS progression

JD Berry, S Paganoni, K Carlson… - Annals of clinical …, 2019 - Wiley Online Library
Objective The amyotrophic lateral sclerosis (ALS) trial outcome measures are clinic based.
Active and passive smartphone data can provide important longitudinal information about …

Speech deterioration in amyotrophic lateral sclerosis (ALS) after manifestation of bulbar symptoms

T Makkonen, H Ruottinen, R Puhto… - … journal of language …, 2018 - Wiley Online Library
Background The symptoms and their progression in amyotrophic lateral sclerosis (ALS) are
typically studied after the diagnosis has been confirmed. However, many people with ALS …

Multimodal speech biomarkers for remote monitoring of ALS disease progression

M Neumann, H Kothare, V Ramanarayanan - Computers in Biology and …, 2024 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that
severely impacts affected persons' speech and motor functions, yet early detection and …

A systematic review and narrative analysis of digital speech biomarkers in Motor Neuron Disease

M Bowden, E Beswick, J Tam, D Perry, A Smith… - NPJ digital …, 2023 - nature.com
Abstract Motor Neuron Disease (MND) is a progressive and largely fatal neurodegeneritve
disorder with a lifetime risk of approximately 1 in 300. At diagnosis, up to 25% of people with …