Beneficial medicinal effects and material applications of rose

H Wang - Heliyon, 2024 - cell.com
Rose is a beautiful and fragrant plant with a variety of medicinal and substance uses.
Various parts of rose such as fruits, flowers, leaves, and bark can be used in various product …

Assessment of methodological pipelines for the determination of isothiocyanates derived from natural sources

S Kyriakou, DT Trafalis, MV Deligiorgi, R Franco… - Antioxidants, 2022 - mdpi.com
Isothiocyanates are biologically active secondary metabolites liberated via enzymatic
hydrolysis of their sulfur enriched precursors, glucosinolates, upon tissue plant disruption …

Sideritis scardica Extracts Demonstrate Neuroprotective Activity against Aβ25–35 Toxicity

A Ververis, K Ioannou, S Kyriakou, N Violaki… - Plants, 2023 - mdpi.com
Alzheimer's disease (AD) is the most prevalent neurodegenerative condition, primarily
affecting seniors. Despite the significant time and money spent over the past few decades …

Chemical Profiling, Antiproliferative and Antimigratory Capacity of Haberlea rhodopensis Extracts in an In Vitro Platform of Various Human Cancer Cell Lines

K Spyridopoulou, S Kyriakou, A Nomikou, A Roupas… - Antioxidants, 2022 - mdpi.com
Haberlea rhodopensis is a Balkan endemic plant that belongs to the Gesneriaceae family,
and is believed to have medicinal use and health-promoting properties. This study aimed to …

(R)-8-Methylsulfinyloctyl isothiocyanate from Nasturtium officinale inhibits LPS-induced immunoinflammatory responses in mouse peritoneal macrophages: chemical …

M Alcarranza, I Villegas, R Recio, R Muñoz-García… - Food & Function, 2023 - pubs.rsc.org
The aim of this study was to develop an optimal synthetic route to obtain natural (R)-8-
methylsulfinyloctyl isothiocyanate ((R)-8-OITC), present in watercress, based on the “DAG …

A naturally derived watercress flower-based phenethyl isothiocyanate-enriched extract induces the activation of intrinsic apoptosis via subcellular ultrastructural and …

S Kyriakou, L Potamiti, N Demosthenous, T Amery… - Nutrients, 2023 - mdpi.com
The aim of the current study was to (i) extract isolated fractions of watercress flowers
enriched in polyphenols, phenethyl isothiocyanate and glucosinolates and (ii) characterize …

Polyphenolics, glucosinolates and isothiocyanates profiling of aerial parts of Nasturtium officinale (Watercress)

S Kyriakou, K Michailidou, T Amery, K Stewart… - Frontiers in plant …, 2022 - frontiersin.org
Watercress (Nasturtium officinale) is a rich source of secondary metabolites with disease-
preventing and/or health-promoting properties. Herein, we have utilized extraction …

Naturally-derived phenethyl isothiocyanate modulates apoptotic induction through regulation of the intrinsic cascade and resulting apoptosome formation in human …

V Tragkola, I Anestopoulos, S Kyriakou… - Toxicology …, 2024 - Taylor & Francis
Malignant melanoma is the most aggressive type of skin cancer with increasing incidence
rates worldwide. On the other hand, watercress is a rich source of phenethyl isothiocyanate …

Naturally Derived Phenethyl Isothiocyanate Modulates Induction of Oxidative Stress via Its N-Acetylated Cysteine Conjugated form in Malignant Melanoma

S Kyriakou, N Demosthenous, T Amery, KJ Stewart… - Antioxidants, 2024 - mdpi.com
Phenethyl isothiocyanate (PEITC) is a secondary metabolic product yielded upon the
hydrolysis of gluconasturtiin and it is highly accumulated in the flowers of watercress. The …

Chemical Characterization and Biological Evaluation of Epilobium parviflorum Extracts in an In Vitro Model of Human Malignant Melanoma

S Kyriakou, V Tragkola, I Paraskevaidis, M Plioukas… - Plants, 2023 - mdpi.com
Malignant melanoma is an aggressive type of skin cancer characterised by high metastatic
capacity and mortality rate. On the other hand, Epilobium parviflorum is known for its …