Monocyte maturation, HIV susceptibility, and transmigration across the blood brain barrier are critical in HIV neuropathogenesis

DW Williams, EA Eugenin, TM Calderon… - Journal of leukocyte …, 2012 - academic.oup.com
ABSTRACT HIV continues to be a global health crisis with more than 34 million people
infected worldwide (UNAIDS: Report on the Global AIDS Epidemic 2010, Geneva, World …

Is HIV-1 evolving to a less virulent form in humans?

KK Ariën, G Vanham, EJ Arts - Nature Reviews Microbiology, 2007 - nature.com
During the rapid spread of HIV-1 in humans, the main (M) group of HIV-1 has evolved into
ten distinct subtypes, undergone countless recombination events and diversified …

[图书][B] Animal models in toxicology

SC Gad - 2006 - taylorfrancis.com
Reflecting more than a decade's worth of changes, Animal Models in Toxicology, Second
Edition is a practical guide to the common statistical problems encountered in toxicology and …

Lentiviral Vpr usurps Cul4–DDB1 [VprBP] E3 ubiquitin ligase to modulate cell cycle

K Hrecka, M Gierszewska… - Proceedings of the …, 2007 - National Acad Sciences
The replication of viruses depends on the cell cycle status of the infected cells. Viruses have
evolved functions that alleviate restrictions imposed on their replication by the host. Vpr, an …

TRIM5 Suppresses Cross-Species Transmission of a Primate Immunodeficiency Virus and Selects for Emergence of Resistant Variants in the New Species

A Kirmaier, F Wu, RM Newman, LR Hall… - PLoS …, 2010 - journals.plos.org
Simian immunodeficiency viruses of sooty mangabeys (SIVsm) are the source of multiple,
successful cross-species transmissions, having given rise to HIV-2 in humans, SIVmac in …

Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS

C Kornfeld, MJY Ploquin, I Pandrea… - The Journal of …, 2005 - Am Soc Clin Investig
T cell activation levels in HIV infection are predictive of AIDS progression. We searched for
the immunological correlates of protection against disease progression by studying the early …

Going wild: lessons from naturally occurring T-lymphotropic lentiviruses

S VandeWoude, C Apetrei - Clinical microbiology reviews, 2006 - Am Soc Microbiol
Over 40 nonhuman primate (NHP) species harbor species-specific simian
immunodeficiency viruses (SIVs). Similarly, more than 20 species of nondomestic felids and …

Macaque models of human infectious disease

MB Gardner, PA Luciw - ILAR journal, 2008 - academic.oup.com
Macaques have served as models for more than 70 human infectious diseases of diverse
etiologies, including a multitude of agents—bacteria, viruses, fungi, parasites, prions. The …

CCR5 as a coreceptor for human immunodeficiency virus and simian immunodeficiency viruses: a prototypic love-hate affair

AJ Jasinska, I Pandrea, C Apetrei - Frontiers in Immunology, 2022 - frontiersin.org
CCR5, a chemokine receptor central for orchestrating lymphocyte/cell migration to the sites
of inflammation and to the immunosurveillance, is involved in the pathogenesis of a wide …

Baby pangolins on my plate: possible lessons to learn from the COVID-19 pandemic

G Volpato, MF Fontefrancesco, P Gruppuso… - Journal of Ethnobiology …, 2020 - Springer
Abstract The Journal of Ethnobiology and Ethnomedicine (JEET), throughout its 15 years of
existence, has tried to provide a respected outlet for scientific knowledge concerning the …