The potential harms and benefits of e‐cigarettes, or electronic nicotine delivery systems
(ENDS), have received significant attention from public health and regulatory communities …

Impaired and limited alveolar regeneration upon injury advances pulmonary disorders and
irreversibly affects millions of people worldwide. Adult mammals do not have a strong …

Acute respiratory distress syndrome (ARDS) contributes to higher mortality worldwide.
Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) have …

Introduction Prophylactic strategies to prevent the development of allergies by establishing
tolerance remain an unmet medical need. We previously reported that the transfer of …

We are developing a series of thiolesters that produce an immediate and sustained reversal
of the deleterious effects of opioids, such as morphine and fentanyl, on ventilation without …

There is an urgent need for development of drugs that are able to reverse the adverse
effects of opioids on breathing and arterial blood-gas (ABG) chemistry while preserving …

The carotid bodies are the primary sensors of blood pH, pO2 and pCO2. The
ganglioglomerular nerve (GGN) provides post-ganglionic sympathetic nerve input to the …

Lung fibrosis (LF) is a chronic progressive, incurable, and debilitating condition of the lung,
which is associated with different lung disease. Treatment options are still sparse …

In vertebrate animals, the automatic, rhythmic pattern of breathing is a highly regulated
process that can be modulated by various behavioral and physiological factors such as …

Cell-penetrant thiol esters including the disulfides, D-cystine diethyl ester and D-cystine
dimethyl ester, and the monosulfide, L-glutathione ethyl ester, prevent and/or reverse the …