Aging is a multifaceted and complicated process, manifested by a decline of normal
physiological functions across tissues and organs, leading to overt frailty, mortality, and …

Mesenchymal stem cells (MSCs) are multipotent cells capable of self-renewal and
differentiation. There is increasing evidence of the therapeutic value of MSCs in various …

A comprehensive understanding of the cellular heterogeneity and molecular mechanisms
underlying the development, homeostasis, and disease of human intervertebral disks (IVDs) …

Adipose‐derived stem cells (ADSCs) can maintain self‐renewal and enhanced
multidifferentiation potential through the release of a variety of paracrine factors and …

Stem cell homing is a multistep endogenous physiologic process that is also used by
exogenously administered hematopoietic stem and progenitor cells (HSPCs). This multistep …

Low back pain is a highly prevalent, chronic, and costly medical condition predominantly
triggered by intervertebral disc degeneration (IDD). IDD is often caused by structural and …

Acute myocardial infarction (AMI) is the leading cause of cardiovascular death and remains
the most common cause of heart failure. Reopening of the occluded artery, ie, reperfusion, is …

BACKGROUND: The use of bone marrow concentrate (BMC) for treatment of
musculoskeletal disorders has become increasingly popular over the last several years, as …

Hyaluronic acid (HA) is a key component of the intervertebral disc (IVD) that is widely
investigated as an IVD biomaterial. One persisting challenge is introducing materials …

Background Human mesenchymal stem cells from dental pulp (hMSC-DP), including dental
pulp stem cells from permanent teeth and exfoliated deciduous teeth, possess unique MSC …