[HTML][HTML] Red blood cell storage lesion: causes and potential clinical consequences

T Yoshida, M Prudent, A D'Alessandro - Blood Transfusion, 2019 - ncbi.nlm.nih.gov
Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …

Red blood cells: a potential delivery system

M Chen, Y Leng, C He, X Li, L Zhao, Y Qu… - Journal of …, 2023 - Springer
Red blood cells (RBCs) are the most abundant cells in the body, possessing unique
biological and physical properties. RBCs have demonstrated outstanding potential as …

Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase …

A D'Alessandro, X Fu, T Kanias, JA Reisz… - …, 2020 - pmc.ncbi.nlm.nih.gov
Red blood cell (RBC) storage in the blood bank promotes the progressive accumulation of
metabolic alterations that may ultimately impact the erythrocyte capacity to cope with oxidant …

Rapid clearance of storage-induced microerythrocytes alters transfusion recovery

C Roussel, A Morel, M Dussiot, M Marin… - Blood, The Journal …, 2021 - ashpublications.org
Permanent availability of red blood cells (RBCs) for transfusion depends on refrigerated
storage, during which morphologically altered RBCs accumulate. Among these, a …

Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage

T Nemkov, K Sun, JA Reisz, A Song, T Yoshida… - …, 2017 - pmc.ncbi.nlm.nih.gov
Hypoxanthine catabolism in vivo is potentially dangerous as it fuels production of urate and,
most importantly, hydrogen peroxide. However, it is unclear whether accumulation of …

Label-free digital holographic microscopy for in vitro cytotoxic effect quantification of organic nanoparticles

KM Eder, A Marzi, Á Barroso, S Ketelhut, B Kemper… - Cells, 2022 - mdpi.com
Cytotoxicity quantification of nanoparticles is commonly performed by biochemical assays to
evaluate their biocompatibility and safety. We explored quantitative phase imaging (QPI) …

Changes in the blood antioxidant defense of advanced age people

M Kozakiewicz, M Kornatowski… - … Interventions in Aging, 2019 - Taylor & Francis
Introduction: Since 1956 there have been numerous scientific articles about free radical
theory of aging which both confirm and deny the theory. Due to oxygen metabolism, there …

Assessing red blood cell deformability from microscopy images using deep learning

ES Lamoureux, E Islamzada, MVJ Wiens, K Matthews… - Lab on a Chip, 2022 - pubs.rsc.org
Red blood cells (RBCs) must be highly deformable to transit through the microvasculature to
deliver oxygen to tissues. The loss of RBC deformability resulting from pathology, natural …

Single cell analysis of stored red blood cells using ultra-high throughput holographic cytometry

HS Park, H Price, S Ceballos, JT Chi, A Wax - Cells, 2021 - mdpi.com
Holographic cytometry is introduced as an ultra-high throughput implementation of
quantitative phase imaging of single cells flowing through parallel microfluidic channels …

Morphology, membrane nanostructure and stiffness for quality assessment of packed red blood cells

E Kozlova, A Chernysh, V Moroz, V Sergunova… - Scientific reports, 2017 - nature.com
Transfusion of packed red blood cells (PRBC) to patients in critical states is often
accompanied by post-transfusion complications. This may be related with disturbance of …