Calcium signalling and transport in the kidney
The kidney plays a pivotal role in regulating calcium levels within the body. Approximately
98% of the filtered calcium is reabsorbed in the nephron, and this process is tightly …
98% of the filtered calcium is reabsorbed in the nephron, and this process is tightly …
[HTML][HTML] Fenestrated Endothelial Cells across Organs: Insights into Kidney Function and Disease
X Mou, SM Leeman, Y Roye, C Miller… - International Journal of …, 2024 - mdpi.com
In the human body, the vascular system plays an indispensable role in maintaining
homeostasis by supplying oxygen and nutrients to cells and organs and facilitating the …
homeostasis by supplying oxygen and nutrients to cells and organs and facilitating the …
Leveraging biomarkers and translational medicine for preclinical safety: Lessons for advancing the validation of alternatives to animal testing
This article explores the potential of principles established in translational medicine for the
use of biomarkers to advance the validation of alternatives to animal testing in preclinical …
use of biomarkers to advance the validation of alternatives to animal testing in preclinical …
Fibrosis‐on‐Chip: A Guide to Recapitulate the Essential Features of Fibrotic Disease
EM Streutker, U Devamoglu, MC Vonk… - Advanced …, 2024 - Wiley Online Library
Fibrosis, which is primarily marked by excessive extracellular matrix (ECM) deposition, is a
pathophysiological process associated with many disorders, which ultimately leads to organ …
pathophysiological process associated with many disorders, which ultimately leads to organ …
Advancements in Kidney-on-Chip: Antibiotic-Induced Kidney Injury and Future Directions
This review paper aims to critically assess the advancements, challenges, and future
prospects of kidney-on-chip (KOC) technology in studying antibiotic-induced kidney injury …
prospects of kidney-on-chip (KOC) technology in studying antibiotic-induced kidney injury …
[HTML][HTML] Advancing healthcare through laboratory on a chip technology: Transforming microorganism identification and diagnostics
CM Ardila - World Journal of Clinical Cases, 2025 - wjgnet.com
In a recent case report in the World Journal of Clinical Cases, emphasized the crucial role of
rapidly and accurately identifying pathogens to optimize patient treatment outcomes …
rapidly and accurately identifying pathogens to optimize patient treatment outcomes …
Mammalian Cell Models of the Distal Convoluted Tubule: A Systematic Review of Cell Lines, Culture Condition and Gene Expression
This review examines the crucial role of human cellular models in renal physiology
research, with a specific focus on the distal convoluted tubule (DCT). It aims to provide a …
research, with a specific focus on the distal convoluted tubule (DCT). It aims to provide a …
Proximal Tubule-on-Chip for Predicting Cation Transport: Dynamic Insights into Drug Transporter Expression and Function
I Petit, Q Faucher, JS Bernard, P Giunchi, A Humeau… - bioRxiv, 2024 - biorxiv.org
Deciphering the sources of variability in drug responses requires to understand the
processes modulating drug pharmacokinetics. However, pharmacological research suffers …
processes modulating drug pharmacokinetics. However, pharmacological research suffers …
[PDF][PDF] Microfluidic Chip for Modeling Ultrafiltration Failure in Peritoneal Dialysis
S Breen - 2024 - digital.wpi.edu
Chronic kidney disease (CKD) causes gradual loss of kidney function in approximately 15%
of US adults [1], where treatment options are either a full organ transplant or routine dialysis …
of US adults [1], where treatment options are either a full organ transplant or routine dialysis …