Development of innovative biomaterials and devices for the treatment of cardiovascular diseases

Y Wang, G Li, L Yang, R Luo, G Guo - Advanced Materials, 2022 - Wiley Online Library
Cardiovascular diseases have become the leading cause of death worldwide. The
increasing burden of cardiovascular diseases has become a major public health problem …

Designing of gradient scaffolds and their applications in tissue regeneration

A Pattnaik, AS Sanket, S Pradhan, R Sahoo, S Das… - Biomaterials, 2023 - Elsevier
Gradient scaffolds are isotropic/anisotropic three-dimensional structures with gradual
transitions in geometry, density, porosity, stiffness, etc., that mimic the biological extracellular …

A smart adhesive Janus hydrogel for non-invasive cardiac repair and tissue adhesion prevention

Y He, Q Li, P Chen, Q Duan, J Zhan, X Cai… - Nature …, 2022 - nature.com
Multifunctional hydrogel with asymmetric and reversible adhesion characteristics is essential
to handle the obstructions towards bioapplications of trauma removal and postoperative …

Engineering complex anisotropic scaffolds beyond simply uniaxial alignment for tissue engineering

J Xing, N Liu, N Xu, W Chen… - Advanced Functional …, 2022 - Wiley Online Library
Anisotropic microarchitectures arising from an aligned organization of threadlike
extracellular matrix (ECM) components or cells are ubiquitous in the human body, such as …

Current applications of polycaprolactone as a scaffold material for heart regeneration

PR Schmitt, KD Dwyer… - ACS Applied Bio Materials, 2022 - ACS Publications
Despite numerous advances in treatments for cardiovascular disease, heart failure (HF)
remains the leading cause of death worldwide. A significant factor contributing to the …

An anisotropic electromagnetic hydrogel promotes cardiomyocyte maturation and post-infarction cardiac repair

X Li, P Lu, Z Liu, Z Wen, X Li, C Wang, W Jin… - Chemical Engineering …, 2023 - Elsevier
Effective therapies for myocardial infarction (MI) are essential in lowering associated
mortality rates. While hydrogel-based patch therapy has shown promise in improving post …

Micropatterned conductive elastomer patch based on poly (glycerol sebacate)-graphene for cardiac tissue repair

M Shi, L Bai, M Xu, Z Li, T Hu, J Hu, Z Zhang, Z Yin… - …, 2022 - iopscience.iop.org
Preparing a micropatterned elastomer film with characteristics that can simulate the
mechanical properties, anisotropy, and electroactivity of natural myocardial tissues is crucial …

Tunable biomaterials for myocardial tissue regeneration: promising new strategies for advanced biointerface control and improved therapeutic outcomes

N Goonoo - Biomaterials Science, 2022 - pubs.rsc.org
Following myocardial infarction (MI) and the natural healing process, the cardiac
mechanostructure changes significantly leading to reduced contractile ability and resulting …

Multi-functional adhesive hydrogel as bio-interface for wireless transient pacemaker

Q Zhang, G Zhao, Z Li, F Guo, Y Huang, G Guo… - Biosensors and …, 2024 - Elsevier
Traditional temporary cardiac pacemakers (TCPs), which employ transcutaneous leads and
external wired power systems are battery-dependent and generally non-absorbable with …

Recent advances in tissue-engineered cardiac scaffolds—the progress and gap in mimicking native myocardium mechanical behaviors

S Baghersad, A Sathish Kumar, MJ Kipper… - Journal of Functional …, 2023 - mdpi.com
Heart failure is the leading cause of death in the US and worldwide. Despite modern
therapy, challenges remain to rescue the damaged organ that contains cells with a very low …