Solvent induced phase inversion-based in situ forming controlled release drug delivery implants

RRS Thakur, HL McMillan, DS Jones - Journal of Controlled Release, 2014 - Elsevier
In situ forming (ISF) drug delivery implants have gained tremendous levels of interest over
the last few decades. This is due to their wide range of biomedical applications such as in …

A review of controlled drug delivery systems based on cells and cell membranes

SM Zargar, DK Hafshejani, A Eskandarinia… - Journal of Medical …, 2019 - journals.lww.com
Novel drug delivery systems have ameliorated drugs' pharmacokinetics and declined
undesired ramifications while led to a better patient compliance by extending the time of …

Injectable drug loaded gelatin based scaffolds as minimally invasive approach for drug delivery system: CNC/PAMAM nanoparticles

K Goodarzi, FJ Shariatzadeh, A Solouk, S Akbari… - European Polymer …, 2020 - Elsevier
Drug delivery systems have been employed to increase efficiency of scaffolds designed for
tissue engineering targets, especially remediating an injury. One step even further is utilizing …

Polymeric nanoparticles modified with fatty acids encapsulating betamethasone for anti-inflammatory treatment

CO Silva, P Rijo, J Molpeceres, IV Figueiredo… - International journal of …, 2015 - Elsevier
Topical glucocorticosteroids were incorporated into nanocarrier-based formulations, to
overcome side effects of conventional formulations and to achieve maximum skin …

An in-situ forming implant formulation of naltrexone with minimum initial burst release using mixture of PLGA copolymers and ethyl heptanoate as an additive: In-vitro …

H Kamali, E Khodaverdi, F Hadizadeh… - Journal of Drug Delivery …, 2018 - Elsevier
An in-situ forming implant formulation of naltrexone (NTX) was achieved based on a
minimum initial burst release of NTX in the in-vitro release medium using a Box-Behnken …

Sustained delivery formulations of risperidone compounds

E Dadey, Q Li, C Lindemann - US Patent 10,010,612, 2018 - Google Patents
Xia et al.(“Uniform biodegradable microparticle systems for con trolled release” in J.
Controlled Release Jul. 18, 2002;(82 (1): 137-147).* Fleischhacker et al.“Treatment of …

Application of artificial neural networks in controlled drug delivery systems

M Rafienia, M Amiri, M Janmaleki… - Applied Artificial …, 2010 - Taylor & Francis
Estimation of release profiles of drugs normally requires time-consuming trial-and-error
experiments. Feed-forward neural networks including multilayer perceptron (MLP), radial …

Sustained release small molecule drug formulation

AS Luk, GH Junnarkar, G Chen - US Patent 10,058,554, 2018 - Google Patents
An injectable depot formulation includes a biocompatible polymer, an organic solvent
combined with the biocompatible polymer to form a viscous gel, and a small molecule drug …

The effect of solvent composition on vancomycin hydrochloride and free base vancomycin release from in situ forming implants

M Darestani‐Farahani… - Polymers for …, 2016 - Wiley Online Library
In situ forming drug delivery systems that are formed by solvent‐induced phase inversion
have attracted extensive attention in sustained delivery of peptides and proteins. Based on …

[PDF][PDF] A review on PLGA based solvent induced in-situ forming implant

A Patel, T Ansari, P Vimal, M Goyani… - Res J Pharm Dos …, 2015 - researchgate.net
SIFI (solvent induced in-situ forming implant) has received remarkable interest in implant
technology over last few decades. SIFI offer a number of advantages over solid implant and …