Filarial worms cause highly morbid diseases such as elephantiasis and river blindness.
Since the 1940s, researchers have conducted vaccine trials in 27 different animal models of …

Introduction Lymphatic filariasis (LF), also known as elephantiasis, has been recognized by
the world health organization and the centers for disease control and prevention as one of …

Lymphatic filariasis affects approximately 3% of the whole world population. Mass drug
administration is currently the major control strategy to eradicate this infection from endemic …

Two cDNAs coding homologous putative metalloproteases (Metis 1 and Metis 2, expected
molecular weights of 55.6 and 56.0 kDa, respectively) were identified from the hard tick …

We have earlier reported identification, expression and purification of a 2.0 kb cDNA clone
coding for Brugia malayi heavy chain myosin which exhibited strong immuno-reactivity with …

In this study filarial recombinant protein or DNA vaccine constructs encoding BmALT-2 and
BmVAH as single or as cocktail antigens were evaluated. Male jirds were immunized …

Lymphatic filariasis, onchocerciasis and loiasis caused by human filarial nematodes are
diseases of tropical and subtropical countries causing considerable morbidity. The available …

Lymphatic filariasis affects nearly 120 million people worldwide and mass preventive
chemotherapy is currently used as a strategy to control this infection. This has substantially …

Present report enumerates the vaccine potential of a glutathione-S-transferase purified from
Setaria cervi against lymphatic filariasis. In jirds (Meriones unguiculatus) vaccination trial, a …

Filariasis is caused by thread-like nematode worms, classified according to their presence in
the vertebrate host. The cutaneous group includes Onchocerca volvulus, Loa loa and …